ASPIRE Blog

Prus K, Weidner K, Alquist C. Therapeutic plasma exchange in adolescent and adult patients with autoimmune neuropsychiatric disorders associated with streptococcal infections. J Clin Apher. 2022 Dec;37(6):597-599. doi: 10.1002/jca.22023. Epub […]

On this weeks episode, I am joined by Dr. Jill Crista. Dr. Jill is a leading expert at the forefront of mold-related illness diagnosis and treatment. During this interview Dr. […]

McMurray KMJ, Sah R. Neuroimmune mechanisms in fear and panic pathophysiology. Front Psychiatry. 2022 Nov 29;13:1015349. doi: 10.3389/fpsyt.2022.1015349. PMID: 36523875; PMCID: PMC9745203. “Currently, our understanding of the role of immune […]

Gabriella True is the President of ASPIRE, Alliance to Solve PANS & Immune-Related Encephalopathies. She and her two children have PANS PANDAS. She has been a leader in the PANS and autism communities since 2008. She focuses on educating about PANS PANDAS while providing crucial support to patients and families living with this disorder.

Supporting the Whole Child – Identifying new pathways to help more children Psychology Today – November 25, 2002 by Sheilah M. Gauch – The Whole Child Key points Educators are […]

In this episode, you will learn about the various contributors to PANDAS and PANS and about solutions to support kids with these challenging conditions.

Hsu TW, Chu CS, Tsai SJ, Bai YM, Su TP, Chen TJ, Chen MH, Liang CS. Risk of Major Mental Disorder after Severe Bacterial Infections in Children and Adolescents: A […]

Speaker: Julie Cox, MSW, LCSW, PLLC Webinar: Helping PANS Families Move From Grief to Empowerment Register to View Recorded Webinar: Watch on Demand Please register even if you will not attend […]

SL O’Dor, S Homayoun, OM.Downer, MA Hamel, JS Zagaroli, KA Williams.A Survey of Demographics, Symptom Course, Family History, and Barriers to Treatment in Children with Pediatric Acute-Onset Neuropsychiatric Disorders and […]

Ranger TA, Clift AK, Patone M, et al. Preexisting Neuropsychiatric Conditions and Associated Risk of Severe COVID-19 Infection and Other Acute Respiratory Infections. JAMA Psychiatry. Published online November 09, 2022. […]

Jyonouchi, H.; Geng, L.; Rossignol, D.A.; Frye, R.E. Long.COVID Syndrome Presenting as Neuropsychiatric Exacerbations in Autism Spectrum Disorder: Insights for Treatment. J. Pers. Med. 2022, 12,1815. https://doi.org/10.3390/jpm12111815 Neurological and neuropsychiatric […]

In PANS patients, all pyschometric endpoints studied exhibited statistically significant decreases following 6 cycles (infusions) of IVIG as well as durability of response for up to 46 weeks in a subset of subjects.

Patients with PANS can benefit from a 6-cycle course of IVIG. Provisional data demonstrate durability of the positive impact of IVG treatment. PANS is an autoimmune disease; innate immunity and the complement system may play a role in the pathogenesis of PANS.