Antibodies for OCD

Immuno-moodulin: A new anxiogenic factor produced by Annexin-A1 transgenic autoimmune-prone T cells

Patients with obsessive compulsive disorder (OCD) have increased levels of Immuno-moodulin (Imood), a protein in their lymphocytes, a type of immune cell.

Anxious mice returned to normal in a couple of days after being given an antibody that blocked Imood. Twenty-three people with OCD and twenty healthy people without OCD were tested; Imood expression was about six times higher in those with OCD. Additional research indicates the same protein, Immod, is elevated in ADHD.

 

 

“There is mounting evidence that the immune system plays an important role in mental disorders. People with auto-immune diseases are known to have higher than average rates of mental health disorders such as anxiety, depression and OCD. Our findings overturn a lot of the conventional thinking about mental health disorders being solely caused by the central nervous system.”

Professor ulvio D’Acquisto, professor of immunology at the University of Roehampton and honorary professor of Immunopharmacology at Queen Mary University of London.

Science Direct

11 comments to Antibodies for OCD

  1. Sarah edmends
    May 1, 2020

    Hi
    My daughter suffers from
    Ocd that has taken over her life at the moment. She is trying ERP which is extremely hard and stressful . I just wondered about these antibody trials and when
    More news would become apparent on whether they work and if so when it would become a available?
    Many thanks

    Reply
    • Gabriella True
      May 1, 2020

      Sent you an email.

      Reply
  2. Jan
    May 21, 2020

    I have the same question as Sarah. When would this anybody treatment become available and where?
    Than you

    Reply
    • Gabriella True
      May 27, 2020

      This is really just the beginning of this information so there is no way to know if or when a test much less treatment will be available.

      Reply
    • Lee
      June 28, 2020

      A close friend of mine has been suffering from OCD for 40-plus years, having tried everything from every med recommended for OCD, along with off-label use of many other meds, to CBT multiple times, to TMS for OCD. OCD is primarily intrusive thinking and my friend is beyond discouraged, not knowing what else to try. Do you have any idea of when trials of this antibody may start or any other information? Any info you could share via email would be so helpful. My dear friend is exhausted and losing hope. Thank you so very much!

      Reply
      • Gabriella True
        July 7, 2020

        I am sorry. We really don’t know. This is very new science and science moves glacially slow. We are not affiliated with the researchers on this study. You could try emailing them directly.

        Reply
        • harpreet Singh
          August 17, 2020

          So How Could I know that the trails have been started to develop antibodies .
          I want to join that if possible .

          Reply
          • Gabriella True
            August 27, 2020

            You would have to contact the authors of the study directly.

  3. amir
    June 3, 2020

    Hi, my name is Amir. I have been suffering from ocd for about 15 years. I followed all the medications, such as Biohoven\’s glutamate and artificial intelligence, and I\’m still undergoing homeopathy.That didn\’t have much effect. But I was hopeful to see this antibody called Imood. I published my email. Let me know.

    Reply
  4. amir
    June 3, 2020

    thank\’s so much

    Reply

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