Kathleen Connery, Marie Tippett, Leanna M. Delhey, Shannon Rose, John C. Slattery, Stephen G. Kahler, Juergen Hahn, Uwe Kruger, Madeleine W. Cunningham, Craig Shimasaki, Richard E. Frye
In an open-labeled IVIG study in children with comorbid ASD and PANS/ PANDAS, anti-tubulin and anti-D2R (as measured by the Cunningham panel) were associated with responsiveness to IVIG treatment, suggesting that these autoantibodies could be biomarkers to select for positive IVIG treatment outcomes. Research continues to explore serum biomarkers and genetic risk factors that can provide a diagnostic tool and/or complement diagnosis in children with PANS/PANDAS.
Megan Huxley, Joshua Stead, Olga Vasieva
Journal of Systems and Integrative Neuroscience-2017
From published and our study it is clear that there is overlap within the IS and NS functions that may be responsible for synergism in inheritable and environmental components in aetiology of a number of neuro-psychiatric disorder, and ASD, in particular.
Dr. Richard Frye, Director of Autism Research at Arkansas Children's Hospital Research Institute, University of Arkansas for Medical Sciences, gives a presentation on neuroimmune aspects of...