The Interagency Autism Coordinating Committee (IACC) is a federal advisory group that coordinates autism research and services within the U.S. Department of Health and Human Services. The Committee...
Examines Lyme disease and co-infections as infectious drivers of neuroinflammation overlapping with autism spectrum disorder.
Reports a cohort of 1,722 children with treatment-resistant ASD and PANS/PANDAS who met clinical criteria for chronic inflammatory response syndrome (CIRS).
Describes improvements in cognition, motor skills, and gastrointestinal function following CIRS-directed therapies.
Identifies a subset of children in tick-endemic regions with Lyme-specific clinical features, diagnosed clinically using CDC criteria.
Notes immune mechanisms including blood–brain barrier disruption, immune imbalance, mitochondrial dysfunction, and microglial priming.
Highlights diagnostic challenges due to limited sensitivity of conventional serologic testing in early or chronic disease.
Sonbol, H.M., Abdelmawgoud, A.S., El-kady, N.M. et al. Serum zonulin level in autistic children and its relation to severity of symptoms a case-control study. Sci Rep 15, 27802 (2025). https://doi.org/10.1038/s41598-025-11420-0
ASPIRE’S Professional Advisory Board publishes PANS/PANDAS Guidelines for Children with Autism PANS PANDAS & Autism Autism PANS Guidelines Children who have autism spectrum disorder (ASD or...
CDC’s Autism Numbers – 1 in 36 The newly published estimated Autism Prevalence rates by the Center for Disease Control and Prevention (CDC) report that 1 in 36 children...
Jyonouchi, H.; Geng, L.; Rossignol, D.A.; Frye, R.E. Long.COVID Syndrome Presenting as Neuropsychiatric Exacerbations in Autism Spectrum Disorder: Insights for Treatment. J. Pers. Med. 2022, 12,1815. https://doi.org/10.3390/jpm12111815
Neurological and neuropsychiatric symptoms are emerging as major long-term sequalae. In patients with pre-existing behavioral symptoms, such as individuals with autism spectrum disorders (ASD), the emergence of neuropsychiatric symptoms due to long COVID can be difficult to diagnose and manage. Herein, we present three ASD cases who presented with markedly worsening neuropsychiatric symptoms following COVID-19 exposure and subsequent difficulty in managing the post-COVID neuropsychiatric symptoms.
CDC’s Autism Numbers The CDC has released the new estimated Autism Prevalence rates. They report that 1 in 44 or 2.27% of American 8-year-olds have an autism spectrum disorder (ASD)...
PANS/PANDAS patients are commonly misdiagnosed with Autism, Tourette’s Syndrome, OCD, bipolar disorder, ADHD, Oppositional Defiance, or with an eating disorder. However, PANS/PANDAS patients can...
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My child was diagnosed at the age of 6 with severe autism. No eye contact, social skills, empathy, poor academic...
It is clear that not enough parents and professionals are educated about PANDAS. My pediatrician apologized to me for not diagnosing my son properly. She said that the children in her practice that...