ASPIRE Blog

This study evaluates the efficacy of naproxen sodium treat OCD symptoms in patients with suspected or diagnosed Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal infections (PANDAS).  

Groundbreaking, Emmy Nominated documentary on PANDAS by Tim Sorel, My My Kid Is Not Crazy: A Search for Hope in the Face of Misdiagnosis is now available for free on Youtube.

ASPIRE cosigned the Association for Accessible Medicines’ letter to the FDA urging them to prioritize patient access to more safe, effective, and affordable complex generic medicines in Generic Drug User Fee Amendment (GDUFA III). Please see the list of other organizations that signed on.å

The PANDAS Physicians Network (PPN) flowcharts for diagnosis and treatment will help clinicians evaluate their patients and determine the best course of treatment. Guidelines and workflows were approved by practitioners […]

Isaac Melamed, Roger H. Kobayashi, Maeve O’Connor, Ai Lan Kobayashi, Andrew Schechterman, Melinda Heffron, Sharon Canterberry, Holly Miranda, and Nazia Rashid.Journal of Child and Adolescent Psychopharmacology. Feb 18, 20210 DOI: […]

As evidenced by her recovery and resolution of symptoms, treating both the Lyme infection and streptococcal infection, as well as treating the underlying autoimmune etiology of her neuropsychiatric symptoms resulted in a successful outcome.

Irina A. Vanzhula, Shruti S. Kinkel-Ram, Cheri A. Levinson. Perfectionism and Difficulty Controlling Thoughts Bridge Eating Disorder and Obsessive-Compulsive Disorder Symptoms: A Network Analysis. Journal of Affective Disorders. Volume 283, […]

Margo Thienemann, Michelle Park, Avis Chan, Jennifer Frankovich. Patients with abrupt early-onset OCD due to PANS tolerate lower doses of antidepressants and antipsychotics. Journal of Psychiatric Research, Vol 135, 2021, […]

These plushy brains are an excellent tool for my son to externalise his worries and concerns. We can take an indirect approach and talk about feelings and concerns without focusing so directly on him.

Sharawat IK, Panda PK, Gupta R. Pediatric Acute-Onset Neuropsychiatric Syndrome with Capgras Syndrome. Ann Indian Acad Neurol. 2021;24(4):600-601. doi:10.4103/aian.AIAN_959_20 This is believed to be the first reported case of Capgras […]

Tetracyclines for COVID-19 Neurological and Neuropsychiatric Manifestations to treat Neuroinflammation Highlights Neuropsychiatric symptoms were reported during COVID-19. Coronaviruses have neuroinvasive potential and induce a potent neuroinflammatory response. Tetracyclines can counteract […]

Cross Amy, Bouboulis Denis, Shimasaki Craig, Jones Charles Ray. Case Report: PANDAS and Persistent Lyme Disease With Neuropsychiatric Symptoms: Treatment, Resolution, and Recovery. Frontiers in Psychiatry. Vol 12, 2021. DOI:10.3389/fpsyt.2021.505941   […]