Allergic diseases influence symptom severity and T lymphocyte subgroups of children with tic disorders

Liu X, Wang X, Zhang X, et al. Allergic diseases influence symptom severity and T lymphocyte subgroups of children with tic disorders.
  • Reviews the severity of tics and T lymphocyte subgroups in patients with tic disorders and allergic diseases
  • 85 children (ages 6-10)- Compared TD but no allergic disease with chronic allergic diseases (including allergic rhinitis, atopic dermatitis, asthma) and tic disorders (TD)
  • Children with TD plus allergic diseases have heavier motor and vocal tic symptoms
  • Children with TD plus allergic diseases had significantly lower levels of CD3, CD4, and CD4:CD8 than those with TD without allergic diseases
  • Allergic disease aggravates imbalance of T lymphocyte subsets and cellular immune

    dysfunction in children with TD
  • Allergic diseases increased illness severity and cellular immune function is increased in children with TD
  • Treat and prevent allergic diseases in children starting at diagnosis of TD

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