Nykytyuk S, Boyarchuk O, Klymnyuk S, Levenets S. The Jarisch-Herxheimer reaction associated with doxycycline in a patient with Lyme arthritis. Reumatologia. 2020;58(5):335-338. doi: 10.5114/reum.2020.99143. Epub 2020 Oct 3. PMID: 33227092; PMCID: PMC7667941.
- A 13-year-old boy developed Lyme arthritis and experienced a severe Jarisch-Herxheimer reaction on day 7 of doxycycline treatment.
- Symptoms included low-grade fever, severe joint and muscle pain, and increased inflammatory markers.
- Unlike the typical mild, short-lived reaction seen in adults, this case was prolonged and intense.
- Raising awareness among healthcare professionals can help differentiate this reaction from allergies or other conditions, improving patient care.
Gabriella True
