Chen, Renfen & Wei, Xiumei. (2021). The interference of laboratory tests by immunoglobulin infusion: Problems and solutions. Journal of Clinical Images and Medical Case Reports. 2. 10.52768/2766-7820/1047.
- IVIG infusion can interfere with a wide range of laboratory tests, leading to inaccurate results.
- The interference stems from the transfer of antibodies and biological agents from donors to patients during IVIG treatment.
- This interference affects tests in infectious disease serology, autoimmune serology, blood bank, haematology, and biochemistry.
- After receiving IVIG (intravenous immunoglobulin), testing for pathogens can be influenced by the antibodies present in the IVIG product. These antibodies may show decreased positivity over time, with the antibodies disappearing approximately 2-4 months after the IVIG treatment ceases. It’s crucial to consider the potential impact of IVIG on testing accuracy and consult with healthcare providers for guidance on the timing and methods of pathogen testing post-IVIG treatment.
Gabriella True
