Lyme Borreliosis and Associations With Mental Disorders and Suicidal Behavior: A Nationwide Danish Cohort Study

Fallon BA, Madsen T, Erlangsen A, Benros ME. Lyme Borreliosis and Associations With Mental Disorders and Suicidal Behavior: A Nationwide Danish Cohort Study. Am J Psychiatry. 2021 Oct 1;178(10):921-931. doi: 10.1176/appi.ajp.2021.20091347. Epub 2021 Jul 28. PMID: 34315282.
  • Results showed that individuals with Lyme borreliosis had higher rates of mental disorders, affective disorders, suicide attempts, and death by suicide compared to those without Lyme borreliosis.
  • The 6-month interval after diagnosis had the highest rate of any mental disorder, and the first 3 years after diagnosis had the highest rate of suicide.
  • Multiple episodes of Lyme borreliosis were associated with increased incidence rate ratios for mental disorders, affective disorders, and suicide attempts.
  • Clinicians should be mindful of the potential psychiatric consequences of Lyme borreliosis, despite the low absolute population risk.

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