Liliia Yukhymenko & Sergii Khomenko & Lidiia Iliukha, 2023. “Diagnosis and monitoring of the functioning of the human nervous system,” Chapters of Monographs, in: Modern methods of diagnosing disaeses, chapter 3, pages 69–94, PC TECHNOLOGY CENTER. Handle: RePEc:baq:pcchap:978-617-7319-65-7-ch3. DOI: 10.15587/978-617-7319-65-7.ch3
“Substantiation of the role of the infectious factor in the pathogenesis of the disease in
Genetic deficiency of folate cycle (GDFC) creates the prerequisites for testing antimicrobial treatment strategies based on a personalized assessment of the patient’s microbial profile. According to this Lisa A. Snider et al. performed a double-blind, placebo-controlled, randomized clinical trial of long-term prophylactic therapy with penicillin VK 250 mg twice daily and azithromycin 250 mg twice daily once a week for 1 year in PANDAS. A 96 % reduction in the frequency of exacerbations of streptococcal infection and a 61 % reduction in the number of relapses of PANDAS in patients treated with both penicillin and azithromycin compared with placebo was demonstrated [98]. It is clear that children with neuro-psychiatric manifestations require antiviral, antifungal and antiprotozoal treatment, in addition to antibiotic therapy, if relevant infectious agents are identified, which should be studied in controlledclinical trials.”
Gabriella True
