Nicolás Lundahl Ciano-Petersen, Sergio Muñiz-Castrillo, Cristina Birzu, Alberto Vogrig, Antonio Farina, Macarena Villagrán-García, Bastien Joubert, Dimitri Psimaras, Jérôme Honnorat, Cytokine dynamics and targeted immunotherapies in autoimmune encephalitis, Brain Communications, Volume 4, Issue 4, 2022, fcac196, https://doi.org/10.1093/braincomms/fcac196
“Autoimmune encephalitides constitute a diverse group of immune-mediated central nervous system disorders mainly characterized by the presence of antibodies targeting neuronal or glial antigens. Despite the notable contribution of antibody discovery to the understanding of their physiopathology, the specific immune cells and inflammatory mediators involved in autoimmune encephalitis are still poorly defined. However, cytokines have recently emerged as crucial signalling molecules in the pathogenesis of autoimmune encephalitis…. Autoimmune encephalitides constitute a diverse group of immune-mediated central nervous system disorders mainly characterized by the presence of antibodies targeting neuronal or glial antigens. Despite the notable contribution of antibody discovery to the understanding of their physiopathology, the specific immune cells and inflammatory mediators involved in autoimmune encephalitis are still poorly defined. However, cytokines have recently emerged as crucial signalling molecules in the pathogenesis of autoimmune encephalitis.”