de Oliveira, K.C., Camilo, C., Gastaldi, V.D. et al. Brain areas involved with obsessive-compulsive disorder present different DNA methylation modulation. BMC Genom Data 22, 45 (2021). DOI:10.1186/s12863-021-00993-0
- Confirms involvement of previously associated genes and biological processes in OCD as well as reports differences related to specific brain areas
- Findings point to a role of cellular communication, inflammatory processes and behavior mediated by DNA methylation in OCD brain tissues.
- Findings were related to the immune system, reaffirming the current literature findings about its involvement with OCD.
- Changes in DNA methylation are involved with OCD and further studies are needed to characterize alterations in different paths in each brain area.