Kiprov DD, A Paradigm Shift in the Utilization of Therapeutic Plasmapheresis in Clinical Practice.
Ann Clin Med Case Rep. 2023; V12(5): 1-7. ISSN 2639-8109 Volume 12
We report our experience in treating patients with TPE on an outpatient basis with several different medical conditions (Alzheimer’s disease, Long Covid, PANDAS) and prophylactically in older individuals for the attenuation of inflammaging.
PANDAS is another condition that is the result of postinfectious autoimmunity mediated through cross-reactive antibodies produced against molecular “mimics” or epitopes on the GAS cells that resemble host antigens [24]. Removal of these autoantibodies with TPE should result in symptomatic improvement.
We treated 7 patients with PANDAS over a period of 2 years. Patients were referred for TPE because they had severe symptoms with marked impairment of function at home, at school
and with peers, and had not responded to treatment with antibiotics, corticosteroids, and high dose IVIG.
Gabriella True
