ASPIRE Blog

Lacy was an outgoing, fun nine-year-old. Then, one night, everything changed. She became a shell of herself.

Her mother, Crystal, 30, from Illinois, told Newsweek she can only describe last year as “hell.” Doctors said her first-born had anxiety and depression — but Crystal’s instincts told her something else was happening.

College with PANS/PANDAS: Your Story Matters Starting college can be challenging for any young adult. For students living with PANS/PANDAS, the transition often comes with added layers—managing health, navigating accommodations, […]

Starting college is an exciting milestone, but for students with PANS/PANDAS, the transition can feel especially overwhelming. Balancing academics, health needs, and independence requires careful planning and support. The good […]

Zoom – Thurs, December 18, 7:00 PM Eastern

Danieli, M.G.; Buti, E.; Longhi, E.; et al. Advancing Our Understanding of IVIg in Pediatric Acute-Onset Neuropsychiatric Syndrome. Journal of Mosaic of Autoimmunity 2025, 1 (2), 5. doi.org/10.53941/jmai.2025.100012 Reviews intravenous […]

Matera M, Biagioli V, Illiceto MT, Palazzi CM, Cavecchia I, Manzi A, Lugli S, Pennazzi L, Meocci M, Pedaci FA, Bertuccioli A. Pediatric acute-onset neuropsychiatric syndromes and the gut-oral-brain axis: […]

Thomas T, Eyre M, Ferrarin E, Newlove-Delgado T, Sie A, Armangue T, Ben-Pazi H, Benrhouma H, Clavenna A, Cardoso F, Dure LS, Jones HF, Gilbert DL, Gulati S, Jiang Y, […]

PANDAS and PANS: Pathophysiology, Diagnostics and Therapeutic Approaches in Pediatric Autoimmune Neuropsychiatric Disorders – a literature review. March 2025. Journal of Education Health and Sport 79:57830. DOI:10.12775/JEHS.2025.79.57830 Identifies a subgroup […]

Rahman SS, Hussein N, Galfrè SG, et al. Sex-associated and disease state-dependent monocyte polarization and CNS-trafficking phenotypes in pediatric acute-onset neuropsychiatric syndrome (PANS). Journal of Neuroinflammation. 2025;22:273.doi:10.1186/s12974-025-03549-6 Characterized circulating monocyte […]

Lång U, Metsälä J, Ramsay H, Boland F, Heikkilä K, Pulakka A, Lawlor A, O’Connor K, Veijola J, Kajantie E, Healy C, Kelleher I. Doxycycline Use in Adolescent Psychiatric Patients […]

DASHORE, Jodie A. et al. Autism Spectrum Disorders and Lyme Disease: Exploring Shared Neuro-Inflammatory and Immune Pathways. Medical Research Archives, [S.l.], v. 13, n. 11, nov. 2025. ISSN 2375-1924. doi: […]

Parents say their children seemingly change overnight, displaying dangerous behaviors that often mimic symptoms of obsessive-compulsive disorder or schizophrenia. However, getting a proper diagnosis can be difficult. Three Louisiana families are sharing their stories to raise awareness about a misunderstood condition often triggered by something as common as strep throat.