Salvucci F, Codella R, Coppola A, et al. Antihistamines improve cardiovascular manifestations and other symptoms of long-COVID attributed to mast cell activation. Front Cardiovasc Med. 2023;10:1202696. doi:10.3389/fcvm.2023.1202696.
Mast cell activation in Long COVID (related work)
-
Observational study evaluating Long COVID patients treated with H1/H2 antihistamines.
-
Reports improvement in fatigue, cognitive symptoms, tachycardia, and other systemic complaints.
-
Supports the hypothesis that mast cell activation contributes to Long COVID symptom persistence.
-
Suggests immune dysregulation—rather than viral persistence—may drive ongoing symptoms in a subset of patients.
Gabriella True
