Sankaranarayanan, Anoop & John, J. (2003). Paediatric autoimmune neuropsychiatric disorders (PANDAS): A case report. The National medical journal of India. 16. 22-3. Read report
In view of the early onset of obsessive symptoms with periodic sudden exacerbations interspersed with periods of partial remissions, and the past history of streptococcal throat infection, the possibility of PANDAS was considered (Table I). However, he did not exhibit any abnormal movement, although he seemed fidgety and restless (Swedo2 has described ‘squirminess’ in some patients). In addition, the ASO titre done at our hospital was negative. It is, however, well accepted that not all exacerbations are preceded by group A beta-haemolytic streptococci (GABHS) infections and a prospective follow up is required to establish this association.
Note: Neither tics nor abnormal movements are required for a PANS diagnosis.
Gabriella True
