Five Youth with Pediatric Acute-Onset Neuropsychiatric Syndrome of Differing Etiologies
Jennifer Frankovich, Margo Thienemann, Sonal Rana, Kiki Chang
Youth with PANS may present in differing ways, with psychiatric and physical symptoms overlapping with inflammatory or infectious diseases, pain syndromes, and other psychiatric diagnoses. Patients’ psychiatric symptoms may respond to treatments targeting the underlying cause of physical illness. Faced with a pediatric patient demonstrating the abrupt onset or exacerbation of psychiatric and physical symptoms, clinicians should consider PANS in their differential diagnosis.