Chronic Fatigue Symptoms in Children with Abrupt Early-onset OCD And/or PANS

Avis Chan 1, Angeline Truong 2, Bahare Farhadian 3, Theresa Willett 2, Melissa Silverman 1, Paula Tran 1, Margo Thienemann 2 and Jennifer Frankovich4, 1Stanford University School of Medicine, Palo Alto, 2Stanford University School of Medicine, Palo Alto, California, 3Stanford Immune Behavioral Health Clinic and PANS Research Program at Lucile Packard Children’s Hospital, Palo Alto, 4Stanford

The 2020 Pediatric Rheumatology Symposium, originally scheduled for April 29 – May 2, was postponed due to COVID-19; therefore, abstracts were not presented as scheduled.

Conclusion: Our study shows that CFS/ME occurs in 1 in 6 patients with AEO-OCD. The prevalence rate is much higher than the general adolescent population (1 in 100-200). This underscores the need to systematically assess fatigue in this group of patients. Future studies should determine possible shared biological underpinnings between AEO-OCD/PANS and CFS/ME.

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