Miro Kovacevic, Paul Grant, Susan E. Swedo JCAP-2015 PDF This case series demonstrates the benefits of IVIG therapy for youths with PANDAS/PANS, including those who had been symptomatic for several […]
Read moreM. Elizabeth Latimer, Nathan L’Etoile, Jakob Seidlitz, Susan E. Swedo JCAP-2015 Therapeutic plasma apheresis is an invasive medical intervention that should be reserved for treatment of children and adolescents who […]
Read moreAjay Kumar, Mitchel Williams, Otto Muzik and Harry Chugani Journal of Nuclear Medicine–2015 Our findings suggest increased activated microglial cells, suggesting underlying neuroinflammation, in bilateral caudate nuclei in children with […]
Read moreKathleen G. Walker, Petrus J. de Vries, Dan J. Stein, and Jo M. Wilmshurst Journal of Child Neurology-2015 In South Africa, and worldwide, rheumatic fever represents a public health problem. […]
Read moreChandra AM, Keilp JG, Fallon BA. Correlates of perceived health-related quality of life in post-treatment Lyme encephalopathy. Psychosomatics. 2013 Nov-Dec;54(6):552-9. doi: 10.1016/j.psym.2013.04.003. Epub 2013 Jul 9. PMID: 23845316; PMCID: PMC5507690. […]
Read moreHornig M. The role of microbes and autoimmunity in the pathogenesis of neuropsychiatric illness. Curr Opin Rheumatol. 2013 Jul;25(4):488-795. doi: 10.1097/BOR.0b013e32836208de. PMID: 23656715. Summary: Microbes, both pathogenic and commensal, can […]
Read moreHornig M, Lipkin WI. Immune-mediated animal models of Tourette syndrome. Neurosci Biobehav Rev. 2013 Jul;37(6):1120-38. doi: 10.1016/j.neubiorev.2013.01.007. “Demonstration of the ability to recreate these abnormalities through passive transfer of serum […]
Read moreJacek E, Fallon BA, Chandra A, Crow MK, Wormser GP, Alaedini A. Increased IFNα activity and differential antibody response in patients with a history of Lyme disease and persistent cognitive […]
Read moreRhee H, Cameron D. Lyme disease and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS): an overview. Int J Gen Med. 2012;5:163-174 https://doi.org/10.2147/IJGM.S24212 B. burgdorferi and GAβHS are very […]
Read moreMurphy TK, Kurlan R, Leckman J. The immunobiology of Tourette’s disorder, pediatric autoimmune neuropsychiatric disorders associated with Streptococcus, and related disorders: a way forward. J Child Adolesc Psychopharmacol. 2010 Aug;20(4):317-31. […]
Read moreYaddanapudi K, Hornig M, Serge R, De Miranda J, Baghban A, Villar G, Lipkin WI. Passive transfer of streptococcus-induced antibodies reproduces behavioral disturbances in a mouse model of pediatric autoimmune […]
Read moreHCP, October 4, 2009 Read Article In addition, patients may be emotionally labile and demonstrate crying, grimacing, or restlessness. Speech often is slurred. These emotional and behavioral changes tend to […]
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