ASPIRE Blog

E. Carla Parker-Athill, Jared Ehrhart, Jun Tan, Tanya K. Murphy JCAP-2015 These findings suggest a role for cytokine dysregulation in the pathogenesis of tic disorders. It also points toward the […]

Carol J. Cox, Amir J. Zuccolo, Erica V. Edwards, Adita Mascaro-Blanco, Kathy Alvarez, Julie Stoner, Kiki Chang, Madeleine W. Cunningham JCAP-2015 Our study suggested a significant correlation of streptococcal-associated tics […]

Miro Kovacevic, Paul Grant, Susan E. Swedo JCAP-2015 PDF This case series demonstrates the benefits of IVIG therapy for youths with PANDAS/PANS, including those who had been symptomatic for several […]

M. Elizabeth Latimer, Nathan L’Etoile, Jakob Seidlitz, Susan E. Swedo JCAP-2015 Therapeutic plasma apheresis is an invasive medical intervention that should be reserved for treatment of children and adolescents who […]

Ajay Kumar, Mitchel Williams, Otto Muzik and Harry Chugani Journal of Nuclear Medicine–2015 Our findings suggest increased activated microglial cells, suggesting underlying neuroinflammation, in bilateral caudate nuclei in children with […]

Kathleen G. Walker, Petrus J. de Vries, Dan J. Stein, and Jo M. Wilmshurst Journal of Child Neurology-2015 In South Africa, and worldwide, rheumatic fever represents a public health problem. […]

Chandra AM, Keilp JG, Fallon BA. Correlates of perceived health-related quality of life in post-treatment Lyme encephalopathy. Psychosomatics. 2013 Nov-Dec;54(6):552-9. doi: 10.1016/j.psym.2013.04.003. Epub 2013 Jul 9. PMID: 23845316; PMCID: PMC5507690. […]

Hornig M. The role of microbes and autoimmunity in the pathogenesis of neuropsychiatric illness. Curr Opin Rheumatol. 2013 Jul;25(4):488-795. doi: 10.1097/BOR.0b013e32836208de. PMID: 23656715. Summary: Microbes, both pathogenic and commensal, can […]

Hornig M, Lipkin WI. Immune-mediated animal models of Tourette syndrome. Neurosci Biobehav Rev. 2013 Jul;37(6):1120-38. doi: 10.1016/j.neubiorev.2013.01.007. “Demonstration of the ability to recreate these abnormalities through passive transfer of serum […]

Jacek E, Fallon BA, Chandra A, Crow MK, Wormser GP, Alaedini A. Increased IFNα activity and differential antibody response in patients with a history of Lyme disease and persistent cognitive […]

Rhee H, Cameron D. Lyme disease and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS): an overview. Int J Gen Med. 2012;5:163-174 https://doi.org/10.2147/IJGM.S24212 B. burgdorferi and GAβHS are very […]

Murphy TK, Kurlan R, Leckman J. The immunobiology of Tourette’s disorder, pediatric autoimmune neuropsychiatric disorders associated with Streptococcus, and related disorders: a way forward. J Child Adolesc Psychopharmacol. 2010 Aug;20(4):317-31. […]