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  • What is PANS?
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  • What is PANS?
    • Definition
    • Causes
    • Syndrome vs Disorder
    • Who Gets PANS/PANDAS?
    • FAQs about PANS PANDAS
    • Team Approach Needed
    • Clinical Urgency of Diagnosing & Treating
    • Caregiver Experience
  • Symptoms & Diagnosis
    • PANS PANDAS Symptoms
    • PANS PANDAS Disease Course
    • PANS PANDAS Symptom Severity
    • Diagnosing PANS and PANDAS
    • Symptom Tracking Tools
    • PANS PANDAS Appointment Preparation
    • PANS PANDAS Information for Clinicians
    • Roadblocks to a PANS PANDAS Diagnosis
  • Treating PANS
    • Treating PANS and PANDAS
    • PANS and PANDAS at School
    • Medications
    • Behavioral Health
    • Additional Therapies
    • Find a Provider
  • Resources
    • PANS PANDAS Brochures & Handouts
    • ASPIRE PANS PANDAS Webinars
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ASPIRE Blog

Cognitive behavioral therapy and acceptance and commitment therapy as augmentation treatment for (PANDAS): A case report

Published: Apr 1, 2017   |   Author: Aspire   |   Category: Blog, Research   |   Tags: CBT  |   No Comments

A.Pozza European Psychiatry-2017 Along with psychiatric and antibiotic medications, CBT may be a valid augmentation strategy for PANDAS to reduce risk of exacerbations and enhance symptom improvement.

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Impact of PANS and PANDAS Exacerbations on Occupational Performance: A Mixed-Methods Study

Published: Mar 1, 2017   |   Author: Aspire   |   Category: Blog, Research   |   Tags: Occupational Therapy  |   No Comments

Janice Trigilio Tona; Sutanuka Bhattacharjya; Denise Calaprice AJOT-2017 Children with PANS present with pervasive occupational performance needs during exacerbation. Children and families may benefit from accommodations to maximize function during […]

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Prospective Longitudinal Analysis of Immune Responses in Pediatric Subjects After Pharyngeal Acquisition of Group A Streptococci

Published: Feb 15, 2017   |   Author: Aspire   |   Category: Blog, Research   |   No Comments

Nicholas D. Hysmith, Edward L. Kaplan, P. Patrick Cleary, Dwight R. Johnson, Thomas A. Penfound, James B. Dale Journal of Pediatric Infectious Disease Society-2017 PDF The prospective study examining the […]

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Improvement of psychiatric symptoms in youth following resolution of sinusitis

Published: Jan 2, 2017   |   Author: Aspire   |   Category: Blog, Research   |   Tags: advisory board  |   No Comments

Talia Mahony, Douglas Sidell, Hayley Gans, Kayla Brown, Bahare Farhadian, Melissa Gustafson, Janell Sherr, Margo Thienemann, Jennifer Frankovich International Journal of Pediatric Otorhinolaryngology-2017 Improvement of psychiatric symptoms correlated with resolution […]

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Restless Legs Syndrome as an Atypical Case of PANDAS?

Published: Jan 1, 2017   |   Author: Aspire   |   Category: Blog, Research   |   No Comments

Tromba V, Spalice A, Lambiase C, Favoriti A and Tancredi G Austin Journal of Clinical Medicine-2017 Our data confirm that patients with suspected restless leg syndrome could present PANDAS.

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The neuropsychological profile of children with basal ganglia encephalitis: a case series

Published: Dec 19, 2016   |   Author: Aspire   |   Category: Blog, Research   |   Tags: basal ganglia encephalitis  |   No Comments

Pawela C, Brunsdon RK, Williams TA, Porter M, Dale RC, Mohammad SS Dev Med Child Neurol-2016 PDF Although based on a small, cross‐sectional case series, our results highlight the potential […]

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Expression of C-Reactive Protein and Serum Amyloid A in Early to Late Manifestations of Lyme Disease

Published: Dec 1, 2016   |   Author: Gabriella True   |   Category: Blog, Research   |   Tags: Chronic Lyme, Lyme Disease  |   No Comments

Uhde M, Ajamian M, Li X, Wormser GP, Marques A, Alaedini A. Expression of C-Reactive Protein and Serum Amyloid A in Early to Late Manifestations of Lyme Disease. Clin Infect […]

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Randomized, Controlled Trial of Intravenous Immunoglobulin for Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections

Published: Oct 2, 2016   |   Author: Aspire   |   Category: Blog, Research   |   Tags: advisory board, IVIG  |   No Comments

Kyle A. Williams, MD, PhD, Susan E. Swedo, MD, Cristan A. Farmer, PhD, Heidi Grantz, LCSW, Paul J. Grant, MD, Precilla D’Souza, CRNP, Rebecca Hommer, MD, Liliya Katsovich, MA, Robert […]

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Microglial Dysregulation in OCD, Tourette Syndrome, and PANDAS

Published: Sep 23, 2016   |   Author: Aspire   |   Category: Blog, Research   |   Tags: OCD, Tourette  |   No Comments

Luciana Frick, Christopher Pittenger, “Microglial Dysregulation in OCD, Tourette Syndrome, and PANDAS”, Journal of Immunology Research, vol. 2016, Article ID 8606057, 8 pages, 2016. https://doi.org/10.1155/2016/8606057 Mechanisms by which microglial abnormalities […]

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Rapid Eye Movement Sleep Abnormalities in Children with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)

Published: Jul 15, 2016   |   Author: Aspire   |   Category: Blog, Research   |   Tags: REM  |   No Comments

Gaughan T, Buckley A, Hommer R, Grant P, Williams K, Leckman JF, Swedo SE J Clin Sleep Med-2016 This study shows various forms of REM sleep motor disinhibition present in […]

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Pediatric Autoimmune Disorders Associated with Streptococcal Infections and Tourette’s Syndrome in Preclinical Studies

Published: Jun 30, 2016   |   Author: Aspire   |   Category: Blog, Research   |   No Comments

Chiara Spinello, Giovanni Laviola and Simone Macrì Frontiers in Neuroscience – 2016 PDF In the present review we discuss the available evidence in preclinical models in support of the link […]

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PANDAS: Baseline Immunoglobulin Levels Predict Achievement of Remission at One Year Following IVIG Therapy

Published: Jun 23, 2016   |   Author: Aspire   |   Category: Blog, Research   |   Tags: IVIG  |   No Comments

David S. Younger, Phyllis A. Mast, and Denis A. Bouboulis Journal of Neurology and Neurosurgery-2016 Children with PANDAS who had baseline low IgA, IgG or IgG subclass levels were more […]

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