Posts by:
Gabriella True

Sharing Hope!
Sharing Hope!

I share our story so you know you are not alone and full healing as possible! My dear daughter 13 is fully healed! I actually came home to this tonight. ...

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Thank You to ASPIRE’s Volunteers!
April 14, 2021
Thank You to ASPIRE’s Volunteers!

ASPIRE Celebrates Volunteer Appreciation Week! ASPIRE volunteers are the heart of our organization, aiming to improve the lives of those affected by PANS PANDAS. Our different backgrounds and...

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Category:  Blog
The interference of laboratory tests by immunoglobulin infusion: Problems and solutions

Chen, Renfen & Wei, Xiumei. (2021). The interference of laboratory tests by immunoglobulin infusion: Problems and solutions. Journal of Clinical Images and Medical Case Reports. 2. 10.52768/2766-7820/1047.

  • IVIG infusion can interfere with a wide range of laboratory tests, leading to inaccurate results.
  • The interference stems from the transfer of antibodies and biological agents from donors to patients during IVIG treatment.
  • This interference affects tests in infectious disease serology, autoimmune serology, blood bank, haematology, and biochemistry.
  • After receiving IVIG (intravenous immunoglobulin), testing for pathogens can be influenced by the antibodies present in the IVIG product. These antibodies may show decreased positivity over time, with the antibodies disappearing approximately 2-4 months after the IVIG treatment ceases. It’s crucial to consider the potential impact of IVIG on testing accuracy and consult with healthcare providers for guidance on the timing and methods of pathogen testing post-IVIG treatment.
Clinical guidance for diagnosis and management of suspected Pediatric Acute‐onset Neuropsychiatric Syndrome in the Nordic countries
Pfeiffer HCV, Wickstrom R, Skov L, Sørensen CB, Sandvig I, Gjone IH, Ygberg S, de Visscher C, Idring Nordstrom S, Herner LB, Hesselmark E, Hedderly T, Lim M, Debes NM. Clinical guidance for diagnosis and management of suspected Pediatric Acute-onset Neuropsychiatric Syndrome in the Nordic countries. Acta Paediatr. 2021 Apr 13. doi: 10.1111/apa.15875. Epub ahead of print. PMID: 33848371.

“Consensus was achieved in the collaboration on work‐up and treatment of patients with paediatric acute‐onset neuropsychiatric syndrome, which we hope will improve and homogenise patient care and enable future collaborative research in the field.”

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Can PANDAS Swear? A Curious Case of Coprolalia in a 15 Year Old Girl Presenting to the Emergency Department

El Tawil, Chady. (2022). Can PANDAS Swear? A Curious Case of Coprolalia in a 15 Year Old Girl presenting to the Emergency Department. 10.52544/2642-7184(X)XXXX.

Abstract: Pediatric autoimmune neuropsychiatric disorders associated with Streptococcal infections, or PANDAS, is a diagnosis of children with an acute and fast onset of obsessions, compulsions or tics succeeding a Group A beta-hemolytic streptococcal infection. Coprolalia is a form of tics where the patient involuntarily says obscene and inappropriate words. We report a case of a 15-year old girl with a history of suspected PANDAS presenting to the emergency department with recurrent coprolalia without signs of a streptococcus infection. PANDAS and other neuropsychiatric syndromes can have different acute presentations. The ED physicians should be familiar with such disorders and presentations