- 79.8% had at least one NSS-BG (neurological soft signs/behaviors).
- Average of 2.1 NSS-BG per patient.
- More NSS-BG = higher global impairment and more symptoms.
- Regression Results:
- NSS-BG correlated with global impairment and symptom count (p=0.045 and p=0.002, respectively).
- No correlation with age or PANS duration at presentation.
- Conclusions: Higher NSS counts were associated with greater overall impairment and higher symptom burden.
- High NSS-BG prevalence in PANS.
- NSS-BG linked to severity, not age.
- Authors conclude NSSs are common in PANS and may reflect underlying neurobiological involvement relevant to diagnosis and severity assessment.
Gabriella True