Gaughan T, Buckley A, Hommer R, Grant P, Williams K, Leckman JF, Swedo SE. Rapid Eye Movement Sleep Abnormalities in Children with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS). J Clin Sleep Med. 2016 Jul 15;12(7):1027-32. doi: 10.5664/jcsm.5942. PMID: 27166296; PMCID: PMC4918985.
- 5 children with PANS (ages 3–10) underwent overnight polysomnography.
- 87% showed sleep abnormalities.
- 12 of 15 had REM sleep motor disinhibition.
- 4 met formal criteria for REM sleep behavior disorder (RBD).
- Only 2 had a normal sleep study.
- Takeaway: REM motor abnormalities appear common in pediatric PANS and may reflect transient central nervous system dysfunction rather than degenerative disease.
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