Monthly Archives:
April 2020

Chasing Ghosts
Chasing Ghosts

For my son, symptom onset was not overnight. He had so many health issues starting the first few weeks of life, which continued throughout his early childhood. His body was in a near-constant state...

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Family Story – It Was Not Autism
Family Story – It Was Not Autism

April 12th, 2019, is a day I will never forget. It was exactly one week after my daughter's 4th birthday, a Friday. Springtime, my favorite time of the year, the buds of my favorite wisteria, were...

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Benefits of IVIG in Pediatric Acute-Onset Neuropsychiatric Syndrome
Benefits of IVIG in Pediatric Acute-Onset Neuropsychiatric Syndrome (2411)

Isaac Melamed, Roger Kobayashi, Maeve O’Connor, Ai Lan Kobayashi, Andrew Schechterman, Melinda Heffron, Sharon Canterberry, Holly Miranda, Nazia Rashid Neurology Apr 14 2020, 94

“Conclusions: In PANS, which may be associated with an underlying immune dysregulation, IVIG [Octagam 5%] successfully ameliorated psychological symptoms and dysfunction, with sustained benefits for at least 8 weeks, and up to 46 weeks, following the final infusion. In addition, baseline immune and autoimmune profiles demonstrated significant elevations in a majority of subjects, which requires further evaluation, characterization, and study to clarify the potential immune dysfunction by which PANS manifests and progresses.”