October 23, 2022
New IVIG Study
In PANS patients, all pyschometric endpoints studied exhibited statistically significant decreases following 6 cycles (infusions) of IVIG as well as durability of response for up to 46 weeks in a...
Posts found in:
Research
July 29, 2021
Toolkit – Current Research Studies Information
The ASPIRE information packet on Advances in Research divides the research into sections in order to make it easy to review current research on a specific topic: JCAP diagnostic and treatment...
February 10, 2021
Kyle Williams, MD PhD: Recent Breakthroughs in PANDAS Research
"One of the most important goals of PANDAS research is to improve diagnostic accuracy. Currently we rely upon clinical evaluation of symptoms to make the diagnosis of PANDAS; ideally we would be able...
June 26, 2020
Susan Swedo, MD on Autoantibody Biomarkers for Basal Ganglia Encephalitis
Dr. Swedo briefly explains the importance of this research and its results. The Frontiers article is an important replication and extension of previous work by Dr. Madeleine Cunningham and her...
June 17, 2020
Antibodies From Children With PANDAS Bind Specifically to CINs and Alter Their Activity
Interview with Christopher Pittenger, MD on the study: Antibodies From Children With PANDAS Bind Specifically to Striatal Cholinergic Interneurons and Alter Their Activity ASPIRE sat down with...
June 16, 2020
Scientists propose explanation for baffling form of childhood OCD
Yale scientists may have found a cause for the sudden onset of obsessive-compulsive disorder (OCD) in some children, they...
June 16, 2020
Yale scientists propose explanation for baffling form of childhood OCD
"Yale scientists may have found a cause for the sudden onset of obsessive-compulsive disorder (OCD) in some children, they report. Pediatric autoimmune neuropsychiatric disorders, or PANDAS, were...
Antibodies From Children With PANDAS Bind Specifically to Striatal Cholinergic Interneurons and Alter Their Activity
Antibodies From Children With PANDAS Bind Specifically to Striatal Cholinergic Interneurons and Alter Their Activity Jian Xu, Rong-Jian Liu, Shaylyn Fahey, Luciana Frick, James Leckman, Flora Vaccarino, Ronald S. Duman, Kyle Williams, Susan Swedo, and Christopher Pittenger. Am Jrnl of Psychiatry 16 Jun 2020 https://doi.org/10.1176/appi.ajp.2020.19070698
See ASPIRE’s interview with Christopher Pittenger, MD, PhD, FAPA, FANA on this study.
April 28, 2020
Antibodies for OCD
Patients with obsessive compulsive disorder (OCD) have increased levels of Immuno-moodulin (Imood), a protein in their lymphocytes, a type of immune cell. Anxious mice returned to normal in a...