February 25, 2025
Restricted Eating & PANS Zoom ChitChat
Zoom - Restricted Eating ChitChat - Tuesday, April 1 - 6:30 PM CT...
Blog
February 19, 2025
Virginia PANS PANDAS Updates
Virginia PANS PANDAS Updates Virginia Alliance for PANS/PANDAS Action (VA4PA) is leading legislative efforts. Please contact them directly for more information. Their website is VA4PA and...
February 18, 2025
Nebraska ChitChat Meet Up
In-Person - Lincoln, NE - Saturday, March 15 - 10:00am-12:00pm...
February 18, 2025
Homeschooling and PANS/PANDAS: Resources for Families
Homeschooling and PANS/PANDAS: Resources for Families Traditional school environments can be challenging for many families navigating PANS/PANDAS. Symptoms such as anxiety, OCD, cognitive...
February 18, 2025
PANS & Eating Disorder/Food Restrictions & Toolkits/Handouts
PANS PANDAS & Eating Disorders/Food Restrictions – Full Packet of Recent studies and Flyer. Please note that the Flyer is also available in two poster sizes...
February 18, 2025
New York/Connecticut ChitChat Meet Up
In-Person - Danbury, CT - Thursday, March 13, 2025 - 10:00 AM...
Fluoxetine promotes IL-10-dependent metabolic defenses to protect from sepsis-induced lethality
Gallant RM, Sanchez KK, Joulia E, Snyder JM, Metallo CM, Ayres JS. Fluoxetine promotes IL-10-dependent metabolic defenses to protect from sepsis-induced lethality. Sci Adv. 2025 Feb 14;11(7):eadu4034. doi: 10.1126/sciadv.adu4034. Epub 2025 Feb 14. PMID: 39951524; PMCID: PMC11827869.
- SSRIs Overview: Among the most prescribed drugs globally, primarily used to enhance serotonergic signaling in the brain.
- Beyond the Brain: SSRIs also impact immune and metabolic functions.
- Infection Protection: Studies show SSRIs, including fluoxetine, protect against infections like sepsis and COVID-19, though mechanisms remain unclear.
- Key Findings on Fluoxetine:Protection is independent of peripheral serotonin.
- Increases circulating interleukin-10 (IL-10) levels.
- IL-10 prevents sepsis-induced hypertriglyceridemia and associated cardiac issues (glucose oxidation impairment, lipid accumulation, ventricular stretch, potential cardiac failure).
- Therapeutic Potential: Fluoxetine’s “off-target” effects offer a protective immunometabolic mechanism with possible clinical applications.
February 14, 2025
Washington State PANS PANDAS Updates
For up-to-date information on Oregon’s legislative action: Make sure to follow NWPPN’s Facebook page for updates and questions. To contact NWWP directly, please email them – NWPPN’s...
February 14, 2025
Resources for Eating Restrictions in PANS/PANDAS
Restricted eating, including Avoidant/Restrictive Food Intake Disorder (ARFID), is a common yet complex challenge for individuals with PANS/PANDAS. Families and patients often struggle to find...
February 12, 2025
Health Insurers Deny 850 Million Claims a Year
The Becks paid $20,000 out-of-pocket in 2023 for Emily’s medical care, including occupational therapy, psychiatric appointments, tests, supplements and medications that insurance wouldn’t pay for...
February 1, 2025
Louisiana Zoom ChitChat
Zoom - Louisiana ChitChat - Thursday, February 27 - 3:00 PM CT...