March 22, 2020
COVID-19 How To Decrease Stress & Anxiety During Physical Distancing
How To Decrease Stress &...
March 21, 2020
COVID-19 Q&A with Dr. Nancy O’Hara
We are so excited to have Nancy O'Hara, MD, MPH, FAAP, a member of the ASPIRE Professional Advisory Board, kick off our series of Q&As on...
March 20, 2020
Protect IDEA and Special Education
It is essential that you contact your state representatives in Congress IMMEDIATELY; significant efforts are underway to remove IDEA obligations at the federal level, as well as other educational...
Oxidative stress and gut-derived lipopolysaccharides in children affected by paediatric autoimmune neuropsychiatric disorders associated with streptococcal infections
Loffredo, L., Spalice, A., Salvatori, F., De Castro, G., Guido, C. A., Zicari, A. M., Ciacci, P., Battaglia, S., Brindisi, G., Ettorre, E., Nocella, C., Salvatori, G., Duse, M., Violi, F., & Carnevale, R. (2020). Oxidative stress and gut-derived lipopolysaccharides in children affected by paediatric autoimmune neuropsychiatric disorders associated with streptococcal infections. BMC pediatrics, 20(1), 127. https://doi.org/10.1186/s12887-020-02026-8
“This study shows that children affected by PANDAS have high circulating levels of sNOX2-dp, isoprostanes and of LPS that could be involved in the process of neuroinflammation.”
PANS PANDAS Rocks
PANS Rocks! Come Join the Fun! Paint Rocks and Spread Awareness! ASPIRE spoke with Michelle Dowd, who has started a fun project for kids with PANS/PANDAS that also helps spread...
Benjamin’s Family
It is clear that not enough parents and professionals are educated about PANDAS. My pediatrician apologized to me for not diagnosing my son properly. She said that the children in her practice that have PANDAS could not function at all and were curled up in a ball and could not go to school. She said she learned a lot that the symptoms can vary in severity, and not all PANDAS kids have the same symptoms.
Benjamin’s PANS PANDAS Story – (not autism)
It is clear that not enough parents and professionals are educated about PANDAS. My pediatrician apologized to me for not diagnosing my son properly. She said that the children in her practice that...
March 13, 2020
Delivery of IEP Services During Corona
Many students with PANS/PANDAS have IEPs. During this period, many schools a being closed for extended periods completely while others are closing temporarily to make plans for remote teaching. The...
March 7, 2020
Enroll in UCONN Study – Families’ Experiences with PANS
University of Connecticut Parents/Caregivers Wanted for a Research Study on Families’ Experiences with PANS (Pediatric Acute-Onset Neuropsychiatric Syndrome) We will be conducting interviews with...
March 3, 2020
ASPIRE & Vitalant Plasma Drive – Nationwide!
Vitalant & ASPIRE Community Plasma Drive March 15 – May 15 – locations throughout the country What to know more about Plasma Donation? ASPIRE has created an easy to understand...
March 2, 2020
PANS: A Diagnosis for My Child’s Sudden Behavior Change
We thought we treated it appropriately. We followed the doctor’s initial recommendations for treating our son’s Lyme disease. He got a little better with the antibiotics but never went back to...
Immuno-moodulin: A new anxiogenic factor produced by Annexin-A1 transgenic autoimmune-prone T cells
GiuseppaPiras, LorenzaRattazzi
Brain, Behavior, and Immunity, 29 February 2020
Patients with obsessive compulsive disorder (OCD) have increased levels of Immuno-moodulin (Imood), a protein in their lymphocytes, a type of immune cell.
Anxious mice returned to normal in a couple of days after being given an antibody that blocked Imood. Twenty-three people with OCD and twenty healthy people without OCD were tested; Imood expression was about six times higher in those with OCD. Additional research indicates the same protein, Immod, is elevated in ADHD.