Elia J, Dell ML, Friedman DF, Zimmerman RA, Balamuth N, Ahmed AA, Pati S. PANDAS with catatonia: a case report. Therapeutic response to lorazepam and plasmapheresis. J Am Acad Child Adolesc Psychiatry. 2005 Nov;44(11):1145-50. doi: 10.1097/01.chi.0000179056.54419.5e. PMID: 16239863.
- Patient: 11-year-old boy with sudden urinary urgency, OCD, severe mood swings, inattention, impulsivity, hyperactivity, and intermittent immobilization.
- Preceding Illness: Fever, cough, ear infection, sinusitis.
- Findings: Elevated ASO & DNAse B titers; MRI showed caudate nuclei swelling.
- Treatment & Outcome: Plasmapheresis rapidly improved OCD and reduced basal ganglia swelling, suggesting an immune-mediated process linked to strep.
- Additional Note: ADHD-like symptoms improved with lorazepam, indicating possible catatonia.
Gabriella True
