Kavanagh E. Long Covid brain fog: a neuroinflammation phenomenon? J Neuroinflammation. 2022;19(1):265. doi:10.1186/s12974-022-02665-6.
Neuroinflammation and Long COVID “brain fog”
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Reviews evidence that persistent cognitive symptoms after COVID are linked to neuroinflammation rather than ongoing viral infection.
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Highlights roles for microglial activation, cytokine signaling, and disrupted neuroimmune regulation.
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Proposes that immune-mediated effects on synaptic function and neuronal metabolism can explain attention, memory, and processing-speed deficits.
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Frames brain fog as a biological inflammatory process, not a psychological or functional complaint.
Gabriella True
