Bartonella spp. Bacteremia and Rheumatic Symptoms in Patients from Lyme Disease–endemic Region

Maggi RG, Mozayeni BR, Pultorak EL, Hegarty BC, Bradley JM, Correa M, Breitschwerdt EB. Bartonella spp. bacteremia and rheumatic symptoms in patients from Lyme disease-endemic region. Emerg Infect Dis. 2012 May;18(5):783-91. doi: 10.3201/eid1805.111366. PMID: 22516098; PMCID: PMC3358077.

  • Bartonella species infection associated with an expanding spectrum of symptoms and lesions
  • Study included 296 patients evaluated by a rheumatologist
  • High prevalence of Bartonella exposure: antibodies in 62%, bacteremia in 41.1%
  • Common prior diagnoses included Lyme disease (46.6%), arthralgia/arthritis (20.6%), chronic fatigue (19.6%), and fibromyalgia (6.1%)
  • B. henselae bacteremia associated with prior neurology referral and neurologic symptoms
  • B. koehlerae bacteremia associated with infectious disease referral
  • Cross-sectional design does not establish causality
  • Authors conclude Bartonella’s potential contribution to neurologic symptoms, joint pain, and progressive arthropathy warrants further study

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