Nurses & PANS PANDAS
May 4, 2020
Nurses & PANS PANDAS

Nurses’ Role in PANS/PANDAS What role do nurses play in helping families with PANS/PANDAS? Nurses are an integral part of the team. Nurses are often the first point of contact...

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Association of Pediatric Acute-Onset Neuropsychiatric Syndrome With Microstructural Differences in Brain Regions Detected via Diffusion-Weighted Magnetic Resonance Imaging

Study: Zheng J, Frankovich J, McKenna ES, et al. Association of Pediatric Acute-Onset Neuropsychiatric Syndrome With Microstructural Differences in Brain Regions Detected via Diffusion-Weighted Magnetic Resonance Imaging. JAMA Network Open. 2020;3(5):e204063. doi:10.1001/jamanetworkopen.2020.4063 

For a more in-depth examination of this study see – Association of PANS With Microstructural Brain Differences on Diffusion MRI Blog

  • Sample: 34 patients with PANS vs 64 controls.
  • Main finding: Higher diffusivity (ADC) across all examined brain regions in PANS, most pronounced in deep gray matter (thalamus, basal ganglia, amygdala).
  • What did not differ: No significant group differences in brain volume; cerebral blood flow differences were limited.
  • Clinical takeaway (authors): DWI may provide quantitative information that could assist the diagnostic workup; further prospective study needed.
Chasing Ghosts
Chasing Ghosts

For my son, symptom onset was not overnight. He had so many health issues starting the first few weeks of life, which continued throughout his early childhood. His body was in a near-constant state...

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Family Story – It Was Not Autism
Family Story – It Was Not Autism

April 12th, 2019, is a day I will never forget. It was exactly one week after my daughter's 4th birthday, a Friday. Springtime, my favorite time of the year, the buds of my favorite wisteria, were...

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