September 26, 2020
We’re not fighting for this for us
"Last week, in part one of our two-part look into PANDAS/PANS, teens Gino Vitelli and Abby Gauch, along with their mothers, told their stories of living with the auto-immune disease. This week, in...
September 24, 2020
He woke up an altogether different child
‘He woke up an altogether different child’: Massachusetts families speak on living with PANDAS/PANS Wicked Local. By James Kukstis. Sep 24, 2020 Part one of our look into PANDAS/PANS Read...
September 2, 2020
IVIG for PANS PANDAS Study
Study To Compare The Effect of Panzyga Versus Placebo in Patients With Pediatric Acute-onset Neuropsychiatric Syndrome. This will be a double blind placebo study of IVIG for...
August 29, 2020
Parent Regulation Cheat Sheet
Elisha Bidwell, LMFT discusses her Parent Regulation Cheat Sheet and how PANS PANDAS caregivers can utilize it. Click to download a printable copy of the Parent Regulation Cheat Sheet Gabriella:...
August 27, 2020
Overview of Lyme & Tick Borne Illness – Dr. Moorcroft
"Education is critical to know what is out there. If we can identify cases of Lyme disease early, we can treat them right away. Then we decrease the likelihood of an infection leading to chronic...
August 27, 2020
Lyme Disease and Tick-Borne Illness Overview – Dr. Moorcroft
According to the CDC, Lyme disease is the number one vector-borne illness in the United States. The CDC believes their typical numbers are underestimating the number of Lyme disease cases in any...
August 27, 2020
Lyme Disease Treatment – Dr. Moorcroft
I often combine antibiotics with natural products, including different antimicrobial herbs and different tinctures. I look at the evidence we have; we're in an evidence-based medical culture, yet we...
August 27, 2020
PANS & Lyme Disease – Dr. Moorcroft
Do I have patients with Lyme triggered PANS? Do I have patients whose Lyme does not trigger PANS symptoms but does exacerbate the severity of pre-existing conditions or make it more difficult to...
August 27, 2020
Bartonella & Babesia – Dr. Moorcroft
In terms of neuropsychiatric symptoms, there are case reports in the medical literature, showing kids who have a PANS presentation who received immunomodulatory treatment, steroids, psychiatric...
Hypoferritinemia and iron deficiency in youth with pediatric acute-onset neuropsychiatric syndrome
Chan, A., Karpel, H., Spartz, E. et al. Hypoferritinemia and iron deficiency in youth with pediatric acute-onset neuropsychiatric syndrome. Pediatr Res 89, 1477–1484 (2021). https://doi.org/10.1038/s41390-020-1103-3
Conclusion: Hypoferritinemia and iron deficiency appear to be more common in PANS patients. More research is needed to confirm and understand this association.
- 79 subjects (mean age of PANS onset of 8.7 years)
- Hypoferritinemia was observed in 27% and three quarters occurred during a PANS flare
- PANS patients with hypoferritinemia had worse global impairment, more comorbid inflammatory diseases, and exhibited a chronic course of PANS illness than those without
- The estimated prevalence of iron deficiency was 3–8% in the PANS cohort, 1.4–2.0-fold higher than in the age- and sex-matched U.S. population.
- Hypoferritinemia was commonly observed during a disease flare but not associated with dietary or demographic factors.
- In patients with PANS and iron deficiency, clinicians should consider possibility of inflammation as the cause especially if iron deficiency cannot be explained by diet and blood loss.
Just Like Any Other Adult!
I am just like any other adult now, thanks to the IViGs and therapy. Do not get me wrong; I have struggled so much with my PANS PANDAS that I have wanted to give up many times. I have cried so hard...