Rare neuropsychiatric condition causes children’s personalities to shift overnight

Researchers identify brain abnormalities in people with PANS

By Tracey Romero

Stanford University researchers have discovered subtle structural differences in the brains of children with a rare condition that seemingly causes their personalities to change overnight.

Children with pediatric acute-onset neuropsychiatric syndrome, or PANS, experience a rapid onset of symptoms, including new obsessions, compulsions and dramatic mood swings and tantrums.