From IVIG to PEX to Rituximab to Helminths to treat PANS
Before We have four kids; two have PANS. Charlie’s came on like a freight train in the summer of 2010 at age 5. Maddie’s PANDAS was a slower unfolding until...
February 21, 2022
PANDAS is Autoimmune Encephalitis
"Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal infection or PANDAS can also be called post-streptococcal autoimmune basal ganglia...
February 19, 2022
Conference: Autoimmune Encephalopathy Secondary to Infectious Disease
Register to Watch Virtually Conference videos are available until May. Please note, if you are having problems accessing the conference, please first check your spam folder for an email...
February 19, 2022
It took me 12 years to get a proper mental health diagnosis. That needs to change | Mental Health Perspectives
The Seattle Times By Leah Penney, Mental Health Perspectives guest columnist “A few weeks after my 6th birthday, I went to bed one night a happy, healthy child, and I...
February 17, 2022
Protecting Your Child from the Child Protection System
What would you do if you thought the government was coming to take your child? Protecting Your Child explains the child protection system—what it is, the way it works, and how to navigate your way...
February 17, 2022
NEDAwareness Week Organizational Partner
One of the primary symptoms of PANS is Severe Eating Restriction. Over 50% of PANS patients will have non-life threatening eating restrictions but more severe than picky eating. While 17% will...
February 15, 2022
Sibling Support
We know there is no parenting playbook; there certainly isn’t one when you add PANS/PANDAS to the mix. As parents, we are often second-guessing our decisions. So, as you read...
Discovering prescription patterns in pediatric acute-onset neuropsychiatric syndrome patients
Lopez Pineda A, Pourshafeie A, Ioannidis A, Leibold CM, Chan AL, Bustamante CD, Frankovich J, Wojcik GL. Discovering prescription patterns in pediatric acute-onset neuropsychiatric syndrome patients. J Biomed Inform. 2021 Jan;113:103664. doi: 10.1016/j.jbi.2020.103664. Epub 2020 Dec 28. PMID: 33359113.
- PANS has an inflammatory or autoimmune etiology associated with an infection.
- Longitudinal clustering can subset patients with polypharmacy treatments.
- Included 43 consecutive new-onset pre-pubertal patients who had at least 3 clinic visits. “We used a cut-off age of 12 years to include only pre-pubertal children, as hormones might play a role in psychiatric symptoms and behaviors.”
- Algorithm identified six clusters with distinct medication usage history which may represent clinician’s practice of treating PANS of different severities and etiologies i.e.,
- two most severe groups requiring high dose intravenous steroids
- two arthritic or inflammatory groups requiring prolonged nonsteroidal anti-inflammatory drug (NSAID)
- two mild relapsing/remitting group treated with a short course of NSAID.
- The psychometric scores as outcomes in each cluster generally improved within the first two years.
Diagnostics, Differential Diagnostics And The Treatment Of Pandas Syndrome – Case Description
Diagnostics, Differential Diagnostics And The Treatment Of Pandas Syndrome – Case Description Mukhtorjonova Khusnigul Nodirbekovna, Tukhtabayeva Kamila Abrarovna, Tashkent Padiatric Medical Institute. World Bulletin of Public Health (WBPH). Volume-6, January 2022. ISSN: 2749-3644
This article gives a case of PANDAS syndrome in an 11-year-old boy. The
course and clinic of the disease in the form of prolonged sneezing attacks
made it difficult to diagnose this syndrome. Conducting biochemical blood
tests, daily video electroencephalographic monitoring (EEG monitoring) and
magnetic resonance imaging of the brain (MRI) allowed to determine the
condition. The appointment of antibiotic therapy and intravenous
administration of immunoglobulin led to remission of the disease. It is
necessary to conduct further studies to determine the effectiveness of the
above drugs for this syndrome.
February 9, 2022
Donate in Memory of
In celebration of the life of In remembrance of life, the family asks that any charitable...
February 8, 2022
Enroll Today – Experience of Caregivers of Children with PANS/PANDAS
Attention Parents and Guardians of children with PANS/PANDAS! The University at Buffalo occupational therapy program is conducting a study of caregiver experiences and stress among parents/guardians...
February 7, 2022
Can OCD Be An Autoimmune Condition?
Examining possible root causes of Obsessive-Compulsive Disorder. Psychology Times by Odelya Gertel Kraybill Ph.D. Key points OCD can be rooted in immune response. OCD can be triggered by infections...