Share Your 2021 Triumphs!
December 14, 2021
Share Your 2021 Triumphs!

Please share your success stories for ASPIRE’s 2021 Triumphs Highlights! We all know PANS PANDAS is rough (understatement) but let’s take a moment to celebrate the successes from the past...

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The relationship between allergic diseases and tic disorders: A systematic review and meta-analysis

J Huang, R Li, L Li, Y Song, L Jin. The relationship between allergic diseases and tic disorders: A systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews, Vol 132, 2022, DOI: 10.1016/j.neubiorev.2021.12.004.

  • Asthma, allergic rhinitis and allergic conjunctivitis are associated with tic disorders.
  • Among subtypes of tic disorders, patients with provisional tic disorder would be more likely to have allergic disease.
  • Shared genetic and etiological factors might account for the association between tic disorders and allergic illness.
Modulating neuroinflammation in COVID-19 patients with obsessive-compulsive disorder

V Nezgovorova, CJ Ferretti, S Pallanti, E Hollander. Modulating neuroinflammation in COVID-19 patients with obsessive-compulsive disorder. Journal of Psychiatric Research, 2021, DOI: 10.1016/j.jpsychires.2021.11.025.

Abstract: Exacerbation of symptoms of obsessive-compulsive disorder (OCD) during COVID-19 or new onset of the OCD symptoms resulting from COVID-19 infection is an understudied area of research. It is possible that increased proinflammatory immune status is associated with the onset of obsessive-compulsive symptoms in patients with COVID-19 and that targeted anti-inflammatory treatments for COVID-19 infection can mitigate the new onset of Obsessive-Compulsive (OC) spectrum symptoms. In this review, we cover OCD pathogenesis as related to COVID-19, summarize the impact of cytokines on behavior, and suggest that anti-cytokine treatments can help mitigate post-COVID-19 and new onset of the OC symptoms.