Connecticut PANS PANDAS Contact Form
December 16, 2025
Connecticut PANS PANDAS Contact Form

Share your contact information to receive updates specific to PANS/PANDAS in Nebraska, including news, events, and advocacy efforts. Rest assured, your information will not be sold or shared, and you...

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Ohio PANS/PANDAS Contact Form
December 16, 2025
Ohio PANS/PANDAS Contact Form

Share your contact information to receive updates specific to PANS/PANDAS in Nebraska, including news, events, and advocacy efforts. Rest assured, your information will not be sold or shared, and you...

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Nebraska PANS PANDAS Contact Form
December 16, 2025
Nebraska PANS PANDAS Contact Form

Share your contact information to receive updates specific to PANS/PANDAS in Nebraska, including news, events, and advocacy efforts. Rest assured, your information will not be sold or shared, and you...

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Missouri PANS PANDAS Contact Form
December 13, 2025
Missouri PANS PANDAS Contact Form

  Share your contact information to receive updates specific to PANS/PANDAS in Missouri, including news, events, and advocacy efforts. Rest assured, your information will not be sold or shared,...

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Doxycycline Use in Adolescent Psychiatric Patients and Risk of Schizophrenia: An Emulated Target Trial
Lång U, Metsälä J, Ramsay H, Boland F, Heikkilä K, Pulakka A, Lawlor A, O’Connor K, Veijola J, Kajantie E, Healy C, Kelleher I. Doxycycline Use in Adolescent Psychiatric Patients and Risk of Schizophrenia: An Emulated Target Trial. Am J Psychiatry. 2025 Nov 5:appiajp20240958. doi: 10.1176/appi.ajp.20240958. Epub ahead of print. PMID: 41190738.
  • Study Overview: Large population-based analysis of >56,000 Finnish adolescents in mental health services who received antibiotics.
  • Key Finding: Doxycycline use linked to 30–35% lower risk of developing schizophrenia in adulthood vs. other antibiotics.
  • Mechanism: May reduce brain inflammation and moderate excessive synaptic pruning, a process tied to schizophrenia.
  • Implications: Suggests repurposing doxycycline as potential early preventive intervention for high-risk youth; needs clinical trials to confirm.