Storch EA, Murphy TK, Geffken GR, Mann G, Adkins J, Merlo LJ, Duke D, Munson M, Swaine Z, Goodman WK. Cognitive-behavioral therapy for PANDAS-related obsessive-compulsive disorder: findings from a preliminary waitlist controlled open trial. J Am Acad Child Adolesc Psychiatry. 2006 Oct;45(10):1171-8. doi: 10.1097/01.chi.0000231973.43966.a0. PMID: 17003662.
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Six of seven children with PANDAS-related OCD improved after CBT; half maintained gains at follow-up.
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Clinician-rated OCD and anxiety severity dropped significantly (large effect sizes: 3.38 and 2.29).
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Self-reported anxiety and depression did not show significant changes.
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Findings suggest CBT is a promising, safe, and minimally invasive treatment for PANDAS-related OCD.
Gabriella True
