April 28, 2020
Antibodies for OCD
Patients with obsessive compulsive disorder (OCD) have increased levels of Immuno-moodulin (Imood), a protein in their lymphocytes, a type of immune cell. Anxious mice returned to normal in a...
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OCD
Benjamin’s PANS PANDAS Story – (not autism)
It is clear that not enough parents and professionals are educated about PANDAS. My pediatrician apologized to me for not diagnosing my son properly. She said that the children in her practice that...
Immuno-moodulin: A new anxiogenic factor produced by Annexin-A1 transgenic autoimmune-prone T cells
GiuseppaPiras, LorenzaRattazzi
Brain, Behavior, and Immunity, 29 February 2020
Patients with obsessive compulsive disorder (OCD) have increased levels of Immuno-moodulin (Imood), a protein in their lymphocytes, a type of immune cell.
Anxious mice returned to normal in a couple of days after being given an antibody that blocked Imood. Twenty-three people with OCD and twenty healthy people without OCD were tested; Imood expression was about six times higher in those with OCD. Additional research indicates the same protein, Immod, is elevated in ADHD.
Obsessive-Compulsive Disorder: Autoimmunity and Neuroinflammation
Mona Gerentes, Antoine Pelissolo, Krishnamoorthy Rajagopal, Ryad Tamouza, Nora Hamdani,
Anxiety Disorders-August 2019
This review highlights that OCD is associated with low-grade inflammation, neural antibodies, and neuro-inflammatory and auto-immune disorders. In some subset of OCD patients, autoimmunity is likely triggered by specific bacterial, viral, or parasitic agents with overlapping surface epitopes in CNS. Hence, subset-profiling in OCD is warranted to benefit from distinct immune-targeted treatment modalities.
Altered frequencies of Th17 and Treg cells in children and adolescents with obsessive-compulsive disorder
Natalia Rodrígueza, Astrid Morerbgh, Azucena González-Navarrocg, Carles Serra-Pages, Daniel Bolo, Teresa Torrese, Albert Martinez-Pinteñoe, Sergi Ma, Amalia Lafuenteegh, Patricia Gassóeg, LuisaLázarobdgh
Brain, Behavior, and Immunity-2019
Highlights
•Th17 cells are increased in children and adolescents with OCD.
•Percentages of Treg cells are reduced in OCD patients.
•Increased levels of Th17 cells are associated with higher severity of OCD symptoms.
•Increased levels of Th17 cells are associated with longer duration of disease.
•Reduced percentatges of Treg cells are associated with longer duration of disease.
July 10, 2019
26th Annual OCD Conference
Come visit ASPIRE at Booth 11! We will be there all weekend talking about PANS and OCD. Come listen to lectures, join support groups, and much...
The E ect of Neuro-feedback on Indicators Obsessive-Compulsive Disorder and Anxiety
Sepideh Shahmoradi, Mohamad Oraky
NeuroQuantology-May 2019
Studies conducted over the past decades showed that neuro-feedback training is effective in the treatment of obsessive-compulsive disorder. Also, the results of this study showed that neuro- feedback had a significant reduction in participants’ anxiety.
August 14, 2017
Small Study Finds Signs of Brain Inflammation in Patients with Obsessive-Compulsive Disorder
In a first-of-its-kind study, researchers have found signs of inflammation within the neurocircuitry associated with adult obsessive-compulsive disorder (OCD). The findings were reported June 21 in...
June 22, 2017
OCD linked to inflammation in the brain
Obsessive-compulsive disorder is an intrusive condition that remains difficult to treat. This is due, in part, to the causes behind the disorder remaining hidden. Recent research, however, points the...