June 3, 2020
Question & Answers with Dr. O’Hara and Vicki Kobliner
Recently Dr. O’Hara and Vicki Kobliner held a Question & Answer zoom meeting for topics including COVID-19, Lyme, PANS...
Blog
Viral Pandemics as Possible Psycho-immunological Causes of Psychiatric Symptoms: From Past to Present
Viral Pandemics as Possible Psycho-immunological Causes of Psychiatric Symptoms: From Past to Present
Aytac HM, Pehlivan S. Viral Pandemics as Possible Psycho-immunological Causes of Psychiatric Symptoms: From Past to Present. Sağlık Bilimlerinde İleri Araştırmalar Dergisi 2020; 3(Suppl.1): S92-S98. https://doi.org/10.26650/JARHS2020-S1-0012
Graduation! A PANS Story
So here we are, graduating by the skin of our teeth. Today with 13 months of sobriety. Just out of another flare in March, as allergies also trigger his immune system, he is holding a job down in a...
May 21, 2020
Lyme Disease and Herbal Treatments – Dr. Wells
Antibiotics are the standard of care for Lyme disease treatment. However, it is reported that 10 to 20% of people continue to suffer from Lyme disease after being diagnosed and given a standard...
Chronic Fatigue Symptoms in Children with Abrupt Early-onset OCD And/or PANS
Avis Chan 1, Angeline Truong 2, Bahare Farhadian 3, Theresa Willett 2, Melissa Silverman 1, Paula Tran 1, Margo Thienemann 2 and Jennifer Frankovich4, 1Stanford University School of Medicine, Palo Alto, 2Stanford University School of Medicine, Palo Alto, California, 3Stanford Immune Behavioral Health Clinic and PANS Research Program at Lucile Packard Children’s Hospital, Palo Alto, 4Stanford
The 2020 Pediatric Rheumatology Symposium, originally scheduled for April 29 – May 2, was postponed due to COVID-19; therefore, abstracts were not presented as scheduled.
Conclusion: Our study shows that CFS/ME occurs in 1 in 6 patients with AEO-OCD. The prevalence rate is much higher than the general adolescent population (1 in 100-200). This underscores the need to systematically assess fatigue in this group of patients. Future studies should determine possible shared biological underpinnings between AEO-OCD/PANS and CFS/ME.
Read Full Abstract.
Case Study – Recovering from PANS, Lyme, CIRS
A Talk with Nathan Who is Recovering from PANS/PANDAS, Lyme & CIRS Gabriella: I had a chat with Dr. Nancy O’Hara, Nathan, and his mom a few years ago and...
May 18, 2020
PANS & Lyme Disease – Dr. Delaney
Lyme disease, PANS, and the Columbia University Lyme & Tick-borne Research Center. Shannon L. Delaney, MD, Director, Child and Adolescent Evaluation, Lyme & Tick-borne Research Center, is a...
May 18, 2020
COVID 19 Antibody Testing
ASPIRE thanks the NECH team for continuing to host talks and having ASPIRE write notes to share with the community. Patients of Dr. O’Hara and Dr. Wells can ask additional...
May 14, 2020
COVID 19 Dysregulation of Immune Response
This was a retrospective study from Wuhan China to examine the dysregulation of the immune response in severe COVID 19 patients using flow cytometry. Of the 452 consecutive patients, 63% were...
Our Rainbow in this Storm
My message to parents is to listen to your child and trust yourself. We all have strong parental instincts for a reason. I know there will be days when all you want to do is hide under the covers and...
May 5, 2020
National Teacher Appreciation Day
So today, we ask YOU to ask your kids this one question: Without Teachers, what would you have never learned. You can ask about teachers in general or one particular teacher. Then post their answers...
Association of Pediatric Acute-Onset Neuropsychiatric Syndrome With Microstructural Differences in Brain Regions Detected via Diffusion-Weighted Magnetic Resonance Imaging
Zheng JFrankovich JMcKenna ES, et al. Association of Pediatric Acute-Onset Neuropsychiatric Syndrome With Microstructural Differences in Brain Regions Detected via Diffusion-Weighted Magnetic Resonance Imaging. JAMA Netw Open. 2020;3(5):e204063. doi:10.1001/jamanetworkopen.2020.4063
In this case-control study of 34 consecutive patients with pediatric acute-onset neuropsychiatric syndrome who had 3 Tesla magnetic resonance imaging, all assessed brain regions, particularly the deep gray matter (eg, the thalamus, basal ganglia, and amygdala), had statistically significantly increased mean diffusivity compared with 64 control participants. These diffusion abnormalities are consistent with the cardinal clinical symptoms of these patients, including obsessions, compulsions, emotional dysregulation, and sleep disturbances.
Meaning Diffusion-weighted magnetic resonance imaging may offer valuable quantitative information to assist with the diagnostic workup of pediatric acute-onset neuropsychiatric syndrome.