Antibiotics are the standard of care for Lyme disease treatment. However, it is reported that 10 to 20% of people continue to suffer from Lyme disease after being diagnosed and given a standard...
Avis Chan 1, Angeline Truong 2, Bahare Farhadian 3, Theresa Willett 2, Melissa Silverman 1, Paula Tran 1, Margo Thienemann 2 and Jennifer Frankovich4, 1Stanford University School of Medicine, Palo Alto, 2Stanford University School of Medicine, Palo Alto, California, 3Stanford Immune Behavioral Health Clinic and PANS Research Program at Lucile Packard Children’s Hospital, Palo Alto, 4Stanford
The 2020 Pediatric Rheumatology Symposium, originally scheduled for April 29 – May 2, was postponed due to COVID-19; therefore, abstracts were not presented as scheduled.
Conclusion: Our study shows that CFS/ME occurs in 1 in 6 patients with AEO-OCD. The prevalence rate is much higher than the general adolescent population (1 in 100-200). This underscores the need to systematically assess fatigue in this group of patients. Future studies should determine possible shared biological underpinnings between AEO-OCD/PANS and CFS/ME.
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A Talk with Nathan Who is Recovering from PANS/PANDAS, Lyme & CIRS Gabriella: I had a chat with Dr. Nancy O’Hara, Nathan, and his mom a few years ago and...
Lyme disease, PANS, and the Columbia University Lyme & Tick-borne Research Center. Shannon L. Delaney, MD, Director, Child and Adolescent Evaluation, Lyme & Tick-borne Research Center, is a...
ASPIRE thanks the NECH team for continuing to host talks and having ASPIRE write notes to share with the community. Patients of Dr. O’Hara and Dr. Wells can ask additional...
This was a retrospective study from Wuhan China to examine the dysregulation of the immune response in severe COVID 19 patients using flow cytometry. Of the 452 consecutive patients, 63% were...
My message to parents is to listen to your child and trust yourself. We all have strong parental instincts for a reason. I know there will be days when all you want to do is hide under the covers and...
Stanford University researchers have discovered subtle structural differences in the brains of children with a rare condition that seemingly causes their personalities to change overnight....
Researchers may have gained new insights into a mystifying condition that causes children's behavior to change so severely and abruptly, it can be like they woke up as a different...
So today, we ask YOU to ask your kids this one question: Without Teachers, what would you have never learned. You can ask about teachers in general or one particular teacher. Then post their answers...
Zheng JFrankovich JMcKenna ES, et al. Association of Pediatric Acute-Onset Neuropsychiatric Syndrome With Microstructural Differences in Brain Regions Detected via Diffusion-Weighted Magnetic Resonance Imaging. JAMA Netw Open. 2020;3(5):e204063. doi:10.1001/jamanetworkopen.2020.4063
In this case-control study of 34 consecutive patients with pediatric acute-onset neuropsychiatric syndrome who had 3 Tesla magnetic resonance imaging, all assessed brain regions, particularly the deep gray matter (eg, the thalamus, basal ganglia, and amygdala), had statistically significantly increased mean diffusivity compared with 64 control participants. These diffusion abnormalities are consistent with the cardinal clinical symptoms of these patients, including obsessions, compulsions, emotional dysregulation, and sleep disturbances.
Meaning Diffusion-weighted magnetic resonance imaging may offer valuable quantitative information to assist with the diagnostic workup of pediatric acute-onset neuropsychiatric syndrome.
Nurses’ Role in PANS/PANDAS What role do nurses play in helping families with PANS/PANDAS? Nurses are an integral part of the team. Nurses are often the first point of contact...