Case Study – Recovering from PANS, Lyme, CIRS
A Talk with Nathan Who is Recovering from PANS/PANDAS, Lyme & CIRS Gabriella: I had a chat with Dr. Nancy O’Hara, Nathan, and his mom a few years ago and...
May 18, 2020
PANS & Lyme Disease – Dr. Delaney
Lyme disease, PANS, and the Columbia University Lyme & Tick-borne Research Center. Shannon L. Delaney, MD, Director, Child and Adolescent Evaluation, Lyme & Tick-borne Research Center, is a...
May 18, 2020
COVID 19 Antibody Testing
ASPIRE thanks the NECH team for continuing to host talks and having ASPIRE write notes to share with the community. Patients of Dr. O’Hara and Dr. Wells can ask additional...
May 14, 2020
COVID 19 Dysregulation of Immune Response
This was a retrospective study from Wuhan China to examine the dysregulation of the immune response in severe COVID 19 patients using flow cytometry. Of the 452 consecutive patients, 63% were...
Our Rainbow in this Storm
My message to parents is to listen to your child and trust yourself. We all have strong parental instincts for a reason. I know there will be days when all you want to do is hide under the covers and...
May 13, 2020
Rare neuropsychiatric condition causes children’s personalities to shift overnight
Stanford University researchers have discovered subtle structural differences in the brains of children with a rare condition that seemingly causes their personalities to change overnight....
May 12, 2020
Sudden Obsessions, Tantrums: What Is PANS in Kids?
Researchers may have gained new insights into a mystifying condition that causes children's behavior to change so severely and abruptly, it can be like they woke up as a different...
May 5, 2020
National Teacher Appreciation Day
So today, we ask YOU to ask your kids this one question: Without Teachers, what would you have never learned. You can ask about teachers in general or one particular teacher. Then post their answers...
Association of Pediatric Acute-Onset Neuropsychiatric Syndrome With Microstructural Differences in Brain Regions Detected via Diffusion-Weighted Magnetic Resonance Imaging
Zheng JFrankovich JMcKenna ES, et al. Association of Pediatric Acute-Onset Neuropsychiatric Syndrome With Microstructural Differences in Brain Regions Detected via Diffusion-Weighted Magnetic Resonance Imaging. JAMA Netw Open. 2020;3(5):e204063. doi:10.1001/jamanetworkopen.2020.4063
In this case-control study of 34 consecutive patients with pediatric acute-onset neuropsychiatric syndrome who had 3 Tesla magnetic resonance imaging, all assessed brain regions, particularly the deep gray matter (eg, the thalamus, basal ganglia, and amygdala), had statistically significantly increased mean diffusivity compared with 64 control participants. These diffusion abnormalities are consistent with the cardinal clinical symptoms of these patients, including obsessions, compulsions, emotional dysregulation, and sleep disturbances.
Meaning Diffusion-weighted magnetic resonance imaging may offer valuable quantitative information to assist with the diagnostic workup of pediatric acute-onset neuropsychiatric syndrome.
May 4, 2020
Nurses & PANS PANDAS
Nurses’ Role in PANS/PANDAS What role do nurses play in helping families with PANS/PANDAS? Nurses are an integral part of the team. Nurses are often the first point of contact...
May 3, 2020
Lyme – Tick Testing
Tick Testing and Disease Transmission Statistics Gabriella: Thank you to Dr. Rich for talking with ASPIRE today about Tick Report and his lab at U Mass. Dr. Rich and I...
May 3, 2020
Lyme Disease – Neurocognitive & Neuropsychiatric Symptoms – Dr. Capanna-Hodge
Neurocognitive and neuropsychiatric symptoms associated with tick-borne disease. Gabriella: Dr. Roseann, thank you for joining ASPIRE to talk about neurocognitive and neuropsychiatric symptoms...