Posts by:
Gabriella True

The Jarisch-Herxheimer reaction associated with doxycycline in a patient with Lyme arthritis
Nykytyuk S, Boyarchuk O, Klymnyuk S, Levenets S. The Jarisch-Herxheimer reaction associated with doxycycline in a patient with Lyme arthritis. Reumatologia. 2020;58(5):335-338. doi: 10.5114/reum.2020.99143. Epub 2020 Oct 3. PMID: 33227092; PMCID: PMC7667941.
  • A 13-year-old boy developed Lyme arthritis and experienced a severe Jarisch-Herxheimer reaction on day 7 of doxycycline treatment.
  • Symptoms included low-grade fever, severe joint and muscle pain, and increased inflammatory markers.
  • Unlike the typical mild, short-lived reaction seen in adults, this case was prolonged and intense.
  • Raising awareness among healthcare professionals can help differentiate this reaction from allergies or other conditions, improving patient care.
Psychosocial Interventions and Immune System Function – A Systematic Review and Meta-analysis of Randomized Clinical Trials
Shields GS, Spahr CM, Slavich GM. Psychosocial Interventions and Immune System Function: A Systematic Review and Meta-analysis of Randomized Clinical Trials. JAMA Psychiatry. 2020 Oct 1;77(10):1031-1043. doi: 10.1001/jamapsychiatry.2020.0431. PMID: 32492090; PMCID: PMC7272116.
  • Inflammation-linked diseases cause over 50% of global deaths. Psychosocial interventions may help, but it’s unclear which work best and for whom.
  • Study: Systematic review and meta-analysis of 56 RCTs (4,060 participants) across 8 psychosocial interventions and 7 immune markers.
  • Findings: Interventions led to a 14.7% improvement in beneficial immune function and 18% reduction in harmful immune activity.
  • Most effective: CBT and combined/multiple interventions, especially those targeting proinflammatory markers.
  • Lasting effects: Benefits persisted at least 6 months post-treatment and held across age, sex, and treatment duration.
  • Conclusion: Psychosocial interventions reliably improve immune function and may be a useful public health strategy.
We’re not fighting for this for us
September 26, 2020
We’re not fighting for this for us

"Last week, in part one of our two-part look into PANDAS/PANS, teens Gino Vitelli and Abby Gauch, along with their mothers, told their stories of living with the auto-immune disease. This week, in...

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Category:  News
He woke up an altogether different child
September 24, 2020
He woke up an altogether different child

‘He woke up an altogether different child’: Massachusetts families speak on living with PANDAS/PANS Wicked Local. By James Kukstis. Sep 24, 2020 Part one of our look into PANDAS/PANS Read...

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Category:  News