Strep throat is a common childhood illness, but in a few children this bacteria infection can lead to alarming, lasting changes in behaviour. Scientists are now starting to unravel how it affects the brain.
Strep throat is a common childhood illness, but in a few children this bacteria infection can lead to alarming, lasting changes in behaviour. Scientists are now starting to unravel how it affects the...
Michigan PANS PANDAS Updates
Current Legislative Action Please visit the MI PANS/PANDAS Alliance to stay updated on how you can take legislative action in Michigan. If you are a Michigan parent of a...
Joint Rebutttal Statement to the AAP
Joint Rebuttal to the American Academy of Pediatrics Clinical Report on PANS (12/16/24)...
Mastering the Art of Swallowing Pills: A Step-by-Step Guide
Swallowing pills can be intimidating for many, especially for those with PANS PANDAS due to OCD, sensory issues, anxiety, or difficulty swallowing. The good news is that with some practice...
Nebraska PANS PANDAS Awareness
🌿 In May, during Mental Health Awareness Month, our Nebraska State Leads—Grace Troupe and Elizabeth Fandl—joined Where There’s a Will Foundation for their annual mental health awareness walk...
Serum zonulin level in autistic children and its relation to severity of symptoms a case-control study
Sonbol, H.M., Abdelmawgoud, A.S., El-kady, N.M. et al. Serum zonulin level in autistic children and its relation to severity of symptoms a case-control study. Sci Rep 15, 27802 (2025). https://doi.org/10.1038/s41598-025-11420-0
- Findings: Children with autism had significantly higher serum zonulin levels (avg. 73 ng/ml) vs. neurotypical controls (avg. 22 ng/ml).
- Correlation: Higher zonulin levels were strongly associated with greater symptom severity (r = 0.9).
- Mechanism: Zonulin regulates tight junctions in the intestinal and blood–brain barriers; elevated levels increase permeability (“leaky gut”), promoting systemic and neuroinflammation.
- Relevance to PANS/PANDAS: Similar barrier dysfunction and inflammation may contribute to symptom flares following infections or immune triggers.
Virginia PANS PANDAS Updates
Virginia PANS PANDAS Updates Virginia Alliance for PANS/PANDAS Action (VA4PA) is leading legislative efforts. Please contact them directly for more information. Their website is VA4PA and...
Mother desperate after insurance denies son’s treatment for coverage with serious brain disease
It’s one of the more common illnesses: strep throat. According to the Centers for Disease Control, strep throat is now at a 20-year high. It is a bacterial infection in your throat and tonsils,...
New York/Connecticut ChitChat Meet Up
In-Person - Danbury, CT - Thursday, June 12 - 10:00am-12:00pm...