A comprehensive, natural approach to treating acute and chronic Lyme disease, from a leading naturopathic physician who has managed his symptoms for more than fifteen...
Lexi’s story exemplifies the absolute devastation patients and families go through as a result of being misdiagnosed for too long. In our article on Clinical Urgency of Diagnosing and Treating,...
Education Seminar All educators are invited to attend a seminar on PANS PANDAS. An overview of symptoms, diagnosis, treatment, and how it affects learning will be provided. Seminar hosted by...
Oroojzadeh, P., Bostanabad, S.Y. & Lotfi, H. Psychobiotics: the Influence of Gut Microbiota on the Gut-Brain Axis in Neurological Disorders. J Mol Neurosci (2022). https://doi.org/10.1007/s12031-022-02053-3
T Bhikram, P Sandor, Neutrophil-lymphocyte ratios as inflammatory biomarkers in psychiatric patients, Brain, Behavior, and Immunity, Volume 105, 2022, Pages 237-246, https://doi.org/10.1016/j.bbi.2022.07.006.
Conclusion: The consistent findings of elevated NLR across the reviewed psychiatric disorders suggest that abnormal NLR is not specific to any one disorder but may reflect a pathological brain process that leads to brain dysfunction. These findings support hypotheses of neuroinflammation being important to the etiology of psychiatric disorders. More research is needed to further elucidate the relationship between specific diagnostic and behavioural constructs and NLR. Future work is also needed to determine the specific neuroinflammatory mechanisms that give rise to specific disorders.
In this companion to Dress Coded, an eighth-grader starts a podcast on climate activism and rallies her friends to create lasting change in their local community and beyond. The First Rule of Climate...
Pourshahid S, Khademolhosseini S, Giri B, et al. (July 12, 2022) A Case of Steroid-Responsive Severe Pneumonia Following a Recent COVID-19 Infection in a Patient With Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infection. Cureus 14(7): e26785. doi:10.7759/cureus.26785
“Drug-induced pneumonitis was a possibility as well; however, she was only taking rituximab and cetirizine. Rituximab is a potential agent for the treatment of pneumonitis refractory to conventional treatments [25]. Although there are a few reported cases of rituximab-induced pneumonitis [26], the three-month delay after the last injection of rituximab and rapid progression in a few days are not consistent with drug-induced pneumonitis.
It is conceivable that her recent COVID-19 infection may have activated an exaggerated inflammatory response as the immunosuppression related to rituximab was subsiding. The rapidly progressing pulmonary consolidations and worsening respiratory symptoms under these circumstances should prompt the clinician to consider steroid-responsive-pneumonia like post-COVID OP, MISA, and IRIS-like reactions. Rapid institution of high-dose steroids seems to be the key to treatment. Whether her history of PANDAS may have further impacted her immune system, making her more prone to this exaggerated response is unclear.”
A landmark exploration of one of the most consequential and mysterious issues of our time: the rise of chronic illness and autoimmune...
The Lady's Handbook for Her Mysterious Illness is a memoir with a mission: to help the millions of (mostly) women who suffer from unnamed or misunderstood conditions - autoimmune illnesses,...
Until recently, microglia were thought to be helpful but rather boring: housekeeper cells in the brain. But a recent groundbreaking discovery has revealed that they connect our physical and mental...
Eat for your mental health and learn the fascinating science behind nutrition with this guide from an expert psychiatrist. Did you know that blueberries can help you cope with the aftereffects of...
Mind Fixers tells the history of psychiatry’s quest to understand the biological basis of mental illness and asks where we need to go from...