Newby MJ, Lane SJ, Haracz K, et al. Occupational performance patterns in children with paediatric acute-onset neuropsychiatric syndrome. Australian Occupational Therapy Journal. 2024;72:e12995. doi:10.1111/1440-1630.12995
Read more in a deeper dive Occupational Performance Fluctuates With PANS Disease State
- Children with PANS show significant declines in occupational performance and socialisation during symptom exacerbations
- Adaptive Behaviour Composite and socialisation scores were significantly lower during exacerbation compared with remission
- During remission, occupational performance returned to age-typical ranges across all measured domains
- Findings highlight the episodic, relapsing–remitting nature of functional impairment in PANS
- Authors emphasize the importance of occupational therapy during flare-ups and caution against assessment-based misinterpretation during exacerbations