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Two-Tier Lyme Disease Serology Test Results Can Vary According to the Specific First-Tier Test Used

Alexandra B Maulden, Aris C Garro, Fran Balamuth, Michael N Levas, Jonathan E Bennett, Desiree N Neville, John A Branda, Lise E Nigrovic, for Pedi Lyme Net, Two-Tier Lyme Disease Serology Test Results Can Vary According to the Specific First-Tier Test Used, Journal of the Pediatric Infectious Diseases Society, Volume 9, Issue 2, June 2020, Pages 128–133, https://doi.org/10.1093/jpids/piy133

Significant variations in two-tier Lyme disease test results were observed in many children, depending on the specific first-tier test utilized. When dealing with children with a strong clinical suspicion of Lyme disease and an initially negative test result, clinicians should contemplate retesting for Lyme disease.

Diagnosis Day
Diagnosis Day

Diagnosis Stories

Do you remember the day your child officially got a diagnosis of PANS/PANDAS? Was it your first doctor? Was it your fifth? Were you devastated? Were you relieved to have an answer and the start of a...

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Autoantibody Biomarkers for Basal Ganglia Encephalitis in Sydenham Chorea and Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infections

Chain Jennifer L., Alvarez Kathy, Mascaro-Blanco Adita, Reim Sean, Bentley Rebecca, Hommer Rebecca, Grant Paul, Leckman James F., Kawikova Ivana, Williams Kyle, Stoner Julie A., Swedo Susan E., Cunningham Madeleine W. Autoantibody Biomarkers for Basal Ganglia Encephalitis in Sydenham Chorea and Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infections. Jnl Frontiers in Psychiatry. Vol.11, 2020. DOI.10.3389/fpsyt.2020.00564   

See Dr. Susan Swedo on new research on Autoantibody Biomarkers for Basal Ganglia Encephalitis for PANDAS and SC

 

We Are Brave – A PANS PANDAS Patient Story
We Are Brave – A PANS PANDAS Patient Story

We Are Brave - A PANS PANDAS Patient Story

I guess my advice for a PANDAS family would to always be there for your sick child. To always tell them that they are brave. Because we are. There may only be 1 in 200 of us, but we are the bravest...

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Antibodies From Children With PANDAS Bind Specifically to Striatal Cholinergic Interneurons and Alter Their Activity

Antibodies From Children With PANDAS Bind Specifically to Striatal Cholinergic Interneurons and Alter Their Activity Jian Xu, Rong-Jian Liu, Shaylyn Fahey, Luciana Frick, James Leckman, Flora Vaccarino, Ronald S. Duman, Kyle Williams, Susan Swedo, and Christopher Pittenger. Am Jrnl of Psychiatry 16 Jun 2020 https://doi.org/10.1176/appi.ajp.2020.19070698

See ASPIRE’s interview with Christopher Pittenger, MD, PhD, FAPA, FANA on this study.