September 26, 2025
NEOMED Brain Day Event – Visit the ASPIRE Vendor Table
NEOMED Brain Day Events – October 8 & 9, 2025 🌿 Brain Day 5K Brisk Walk Wednesday, Oct 8 | 5–7 p.m. | NEOMED Courtyard | $10 Join a fun,...
Blog
September 20, 2025
Louisiana PANS PANDAS Updates
Louisiana PANS PANDAS Action The Louisiana PANS PANDAS Action Committee (LPPA) is a newly formed group that is leading the charge for legislative change in the state to support those...
When Overnight Everything Changed: A Parent’s Perspective on PANS/PANDAS
Sometimes what looks like an eating disorder is really a symptom of PANS/PANDAS. Too many families miss the real cause and go without the help their kids need. That’s why we’re so glad @F.E.A.S.T...
September 6, 2025
Georgia PANS PANDAS Action Updates
SB5 Passes! Bill SB 5 – Status Update Bill Language: Read PDF Note: Key details begin in Part II, Section 2-1 Passed: 04/04/2025 A BILL to be entitled an Act...
Fifteen Years Misdiagnosed: My PANS Journey
⚠️ Trigger Warning: This story contains references to self-harm, suicidal thoughts, and substance use. Mature audiences only. ⚠️ A young adult endured years of psychiatric hospitalizations,...
August 25, 2025
Strep throat is a common childhood illness, but in a few children this bacteria infection can lead to alarming, lasting changes in behaviour. Scientists are now starting to unravel how it affects the brain.
Strep throat is a common childhood illness, but in a few children this bacteria infection can lead to alarming, lasting changes in behaviour. Scientists are now starting to unravel how it affects the...
August 18, 2025
Michigan PANS PANDAS Updates
Current Legislative Action Please visit the MI PANS/PANDAS Alliance to stay updated on how you can take legislative action in Michigan. If you are a Michigan parent of a...
August 12, 2025
Joint Rebutttal Statement to the AAP
Joint Rebuttal to the American Academy of Pediatrics Clinical Report on PANS (12/16/24)...
August 8, 2025
Mastering the Art of Swallowing Pills: A Step-by-Step Guide
Swallowing pills can be intimidating for many, especially for those with PANS PANDAS due to OCD, sensory issues, anxiety, or difficulty swallowing. The good news is that with some practice...
July 30, 2025
Nebraska PANS PANDAS Awareness
🌿 In May, during Mental Health Awareness Month, our Nebraska State Leads—Grace Troupe and Elizabeth Fandl—joined Where There’s a Will Foundation for their annual mental health awareness walk...
Serum zonulin level in autistic children and its relation to severity of symptoms a case-control study
Sonbol, H.M., Abdelmawgoud, A.S., El-kady, N.M. et al. Serum zonulin level in autistic children and its relation to severity of symptoms a case-control study. Sci Rep 15, 27802 (2025). https://doi.org/10.1038/s41598-025-11420-0
- Findings: Children with autism had significantly higher serum zonulin levels (avg. 73 ng/ml) vs. neurotypical controls (avg. 22 ng/ml).
- Correlation: Higher zonulin levels were strongly associated with greater symptom severity (r = 0.9).
- Mechanism: Zonulin regulates tight junctions in the intestinal and blood–brain barriers; elevated levels increase permeability (“leaky gut”), promoting systemic and neuroinflammation.
- Relevance to PANS/PANDAS: Similar barrier dysfunction and inflammation may contribute to symptom flares following infections or immune triggers.