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Gabriella True

Neuropsychiatric consequences of childhood group A streptococcal infection: A systematic review of preclinical models

Santiago Mora, Elena Martín-González, Pilar Flores, Margarita Moreno
Brain, Behavior, and Immunity-2019

Preclinical Animal Models are advancing our knowledge of Post-Infectious BGE

  • Preclinical GAS exposure induced behavioural abnormalities in different paradigms
  • Alterations induced by preclinical GAS exposure resemble those by LPS and Poly I:C.
  • Preclinical GAS exposure increase vulnerability to neuropsychiatric disorders.
  • Preclinical GAS exposure is a valid model for studying streptococcal consequences.
Precision medicine: retrospective chart review and data analysis of 200 patients on dapsone combination therapy for chronic Lyme disease/post-treatment Lyme disease syndrome: part 1
Horowitz RI, Freeman PR. Precision medicine: retrospective chart review and data analysis of 200 patients on dapsone combination therapy for chronic Lyme disease/post-treatment Lyme disease syndrome: part 1. Int J Gen Med. 2019 Feb 18;12:101-119. doi: 10.2147/IJGM.S193608. PMID: 30863136; PMCID: PMC6388746.
Diaminodiphenyl sulfone (DDS CT) decreased eight major Lyme symptoms severity and improved treatment outcomes among patients with chronic Lyme disease/PTLDS and associated coinfections.
Is it PANDAS?
January 1, 2019
Is it PANDAS?

There’s nothing black and white about this mysterious and controversial diagnosis. If your child suffers sudden mental health problems following a case of strep throat, this autoimmune condition...

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