September 29, 2022
What are PANS/PANDAS? 5 Things You Should Know
Seacoast Moms By Amber Buttermore – September 29, 202 If you are wondering, what are PANS/PANDAS, I am here to inform. Here are five things you should know about a...
September 28, 2022
What do you want people to know about PANS PANDAS?
Please help ASPIRE with a PANS Awareness Day project. Please submit one or two sentences on “What do you want people to know about PANS/PANDAS?” via the form below. We...
Long Covid brain fog: a neuroinflammation phenomenon?
Kavanagh E. Long Covid brain fog: a neuroinflammation phenomenon? J Neuroinflammation. 2022;19(1):265. doi:10.1186/s12974-022-02665-6.
Neuroinflammation and Long COVID “brain fog”
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Reviews evidence that persistent cognitive symptoms after COVID are linked to neuroinflammation rather than ongoing viral infection.
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Highlights roles for microglial activation, cytokine signaling, and disrupted neuroimmune regulation.
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Proposes that immune-mediated effects on synaptic function and neuronal metabolism can explain attention, memory, and processing-speed deficits.
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Frames brain fog as a biological inflammatory process, not a psychological or functional complaint.
September 25, 2022
Webinar – Craig Shimasaki, PHd, MBA – Can Infections Really Trigger Neuropsychiatric and Behavioral Disorders?
Speaker: Craig Shimasaki, PHd, MBA Webinar: Can Infections Really Trigger Neuropsychiatric and Behavioral Disorders? Understanding a Biological Basis for Autoimmune Attacks on the Brain Register to...
Correlation between COVID-19 severity and previous exposure of patients to Borrelia spp.
Szewczyk-Dąbrowska, A., Budziar, W., Harhala, M. et al. Correlation between COVID-19 severity and previous exposure of patients to Borrelia spp.. Sci Rep 12, 15944 (2022). https://doi.org/10.1038/s41598-022-20202-x
Also, read Medical News Today article.
- In this study, all hospitalized COVID-19 patients tested positive for Borrelia burgdorferi-specific IgG, with significantly higher levels in severe cases.
- Patients with a history of Borrelia exposure showed increased susceptibility to severe COVID-19 upon SARS-CoV-2 infection.
- Severe COVID-19 patients also exhibited higher levels of IgGs specific to Anaplasma antigens, suggesting a potential link between increased COVID-19 risks and tick bites and related infections.
- Testing for Borrelia-specific IgM revealed higher positivity in hospitalized COVID-19 patients compared to mild/asymptomatic patients and those not infected with SARS-CoV-2. Logistic regression analysis indicated that the odds of COVID-19 hospitalization increased with each positive read for a Lyme disease-related antigen for IgG antibodies.
- Multivariate analysis highlighted specific Borrelia antigens associated with increased odds of hospitalization for both IgG and IgM antibodies. These findings suggest a potential connection between Borrelia exposure and the severity of COVID-19 outcomes.
September 22, 2022
Wake Forest board proclaims PANDAS month, approves rezoning, housing plan
WAKE FOREST — A touching video featuring Jason Wilson, or Jay Jay, led Wake Forest commissioners into their monthly meeting Tuesday, Sept....
A consistent lack of sleep negatively impacts immune stem cells, increasing risk of inflammatory disorders and heart disease.
The Mount Sinai Hospital / Mount Sinai School of Medicine. “A consistent lack of sleep negatively impacts immune stem cells, increasing risk of inflammatory disorders and heart disease.” ScienceDaily. ScienceDaily, 21 September 2022. <www.sciencedaily.com
September 19, 2022
The Invisible Cost Of Caring For A Child With A Health Condition
“So many people say, ‘What are you doing for yourself?’ which is a nice sentiment, but it just further divides me and those people,” Taylor said. “What they don’t understand is that I...
September 16, 2022
The big idea: should we drop the distinction between mental and physical health?
The current false dichotomy holds back research and stigmatises...
Roles of Th17 cytokines in microglial and neurovascular responses to recurrent intranasal Streptococcus pyogenes infections
Wayne, Charlotte Remy. Roles of Th17 cytokines in microglial and neurovascular responses to recurrent intranasal Streptococcus pyogenes infections. 2022 Theses Doctoral. Columbia Academic Commons. https://doi.org/10.7916/62va-6330
Academic Units: Cellular, Molecular and Biomedical Studies
Thesis Advisors: Agalliu, Dritan
Degree: Ph.D., Columbia University
Published: September 7, 2022
September 9, 2022
Somewhere in There: Families Living with PANS & PANDAS Share Their Journeys from Despair to Hope
In stories of heartbreak and healing, they describe how the symptoms of these disorders really look behind closed doors and how relentlessly fighting for the right diagnosis and treatment led their...
A letter to my 14 year old self
Our friend gave ASPIRE permission to share this letter to her 14-year-old self. Many of us know how it feels to be too affected by PANS/PANDAS/BGE to go to school....