July 20, 2018
PANDAS ABC 20/20 Part 1
Parents fear for young daughter's safety as her behavior changes dramatically; Rare disorder may explain 11-year-old's sudden odd tics and moodiness; Why is PANDAS so controversial? Medical...
July 18, 2018
What is PANDAS, the disorder some doctors say can cause extreme behavioral changes in kids? – ABC
Alexia Baier was an eager-to-learn, 4-year-old girl beginning pre-K in a suburb outside of Chicago. She thrived academically — counting, painting and playing with other children. But five...
July 18, 2018
Mystery Diagnosis, Children Under Attack – ABC 20/20 Part 2
Kids Suffer From Debilitating Episodes After Recovering From Strep Throat; Parents Of Kids Diagnosed With PANDAS Face Skepticism From Some Doctors...
Intravenous immunoglobulin for the treatment of autoimmune encephalopathy in children with autism
Kathleen Connery, Marie Tippett, Leanna M. Delhey, Shannon Rose, John C. Slattery, Stephen G. Kahler, Juergen Hahn, Uwe Kruger, Madeleine W. Cunningham, Craig Shimasaki, Richard E. Frye
Transl Psychiatry-2018
In an open-labeled IVIG study in children with comorbid ASD and PANS/ PANDAS, anti-tubulin and anti-D2R (as measured by the Cunningham panel) were associated with responsiveness to IVIG treatment, suggesting that these autoantibodies could be biomarkers to select for positive IVIG treatment outcomes. Research continues to explore serum biomarkers and genetic risk factors that can provide a diagnostic tool and/or complement diagnosis in children with PANS/PANDAS.
June 1, 2018
Twenty years of PANDAS/PANS – Trifiletti
2018 is the 20th anniversary of the introduction of the concept of PANDAS, the notion that specific psychiatric symptoms (motor tics and OCD) can be associated with a specific infectious disease...
May 29, 2018
UK PANDAS & PANS Treatment Guidelines Children’s e-Hospital
Dr Tim Ubhi discusses the recent publication of the first UK treatment guidelines by the UK PANDAS & PANS Physicians...
Borrelia burgdorferi adhere to blood vessels in the dura mater and are associated with increased meningeal T cells during murine disseminated borreliosis
li Divan, Timothy Casselli, S. Anand Narayanan, Sanjib Mukherjee, David C. Zawieja, John A. Watt, Catherine A. Brissette, M. Karen Newell-Rogers, Published: May 3, 2018. https://doi.org/10.1371/journal.pone.0196893
Traditionally, mice haven’t shown neuroborreliosis, mirroring human symptoms, but this study achieved colonization of the central nervous system in mice. Using two strains of B. burgdorferi, researchers infected mice through the skin, consistently detecting spirochetes in the brain membranes 75 days post-infection. Live spirochetes were present, adhering to blood vessels, indicating long-term infection. The presence of CD3+ T cells suggested an immune response. These findings provide new avenues for studying neuroborreliosis and may offer insights into potential treatments for patients.
May 1, 2018
Dr. Frid: PANS/PANDAS – Unraveling Mysteries of Neuropsychiatric Disorders
Dr. Elena Frid speaks on current testing methods and available treatments for PANS/PANDAS during AONM (Academy of Nutritional Medicine) in UK in May of...
April 29, 2018
The Unsung Psychiatric Impact of Strep Throat
Is your child mentally ill? Maybe not. Overnight, a child transforms from happy-go-lucky to anxious, irritable, and obsessive. It seems to the family that the child must have been possessed in...
April 20, 2018
Tara Hunkin – The Basics of PANS / PANDAS Your Questions Answered
I’m Tara Hunkin, Nutritional Therapy Practitioner, Certified GAPS Practitioner, Restorative Wellness Practitioner, mother, and founder of My Child Will Thrive. I am passionate about helping parents...
March 15, 2018
Pediatrics Grand Rounds with Dr Sue Swedo – University of Wisconsin
Pediatrics Grand Rounds with Dr. Sue Swedo Watch Grand...
PANDAS and anorexia nervosa-a spotters’ guide: Suggestions for medical assessment
Vincenzi B, O’Toole J, Lask B. PANDAS and anorexia nervosa–a spotters’ guide: suggestions for medical assessment. Eur Eat Disord Rev. 2010 Mar;18(2):116-23. doi: 10.1002/erv.977. PMID: 20148396.
Conclusion: Given the current state of knowledge, diagnosingPANDAS is extraordinarily difficult. However, extrapolating from knowledge aboutSydenham’s choreaandPANDAS–OCD and PANDAS–tics/TS, a heightened index of suspicion for the existence of an auto-immune reaction in the brain response to environmental infectious agents culminating in ‘anorexia nervosa’ should be maintained.