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Tick-Borne

Lyme disease and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS): an overview

Rhee H, Cameron D. Lyme disease and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS): an overview. Int J Gen Med. 2012;5:163-174
https://doi.org/10.2147/IJGM.S24212

B. burgdorferi and GAβHS are very different microorganisms that evade the immune system and invade a wide variety of tissues, including the central nervous system (CNS). Lyme and PANS can have periods of active disease and periods of remission. Both infections cause physical, neurological, and cognitive symptoms.

The neuropsychiatric manifestations of Lyme borreliosis
Fallon BA, Nields JA, Burrascano JJ, Liegner K, DelBene D, Liebowitz MR. The neuropsychiatric manifestations of Lyme borreliosis. Psychiatr Q. 1992 Spring;63(1):95-117. doi: 10.1007/BF01064684. PMID: 1438607.
  • Lyme disease is a growing tick-borne illness affecting multiple systems.
  • While its neurological effects are well documented, its psychiatric symptoms are less recognized. This paper reviews Lyme’s neuropsychiatric impact and key research.
  • It also explores common psychiatric symptoms, patient challenges, and clinical guidance.