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TMS

Transcranial magnetic stimulation for developmental neuropsychiatric disorders with inflammation

Vaishnavi S. Transcranial magnetic stimulation for developmental neuropsychiatric disorders with inflammation. Developmental Neuroscience. 2023;45(6):342–348. doi:10.1159/000535103

  • Reviews transcranial magnetic stimulation (TMS) as a noninvasive technique that induces electrical changes in the brain via magnetic fields.Describes how repetitive TMS can modulate synaptic and network-level plasticity.

  • Notes that inflammation negatively affects synaptic plasticity and that TMS may help address inflammation-related dysfunction.

  • Summarizes evidence suggesting TMS may directly downregulate inflammatory processes.

  • Highlights potential utility of TMS for neuropsychiatric symptoms in inflammatory neurodevelopmental disorders, including autism, Tourette syndrome, and OCD.

  • Emphasizes that TMS is best viewed as a technology platform for modulating dysfunctional brain networks and may expand as understanding of network dysfunction grows